Speciation, Characterization and Antifungal Susceptibility Pattern of Candida Species
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Introduction: The incidence of Candida has been on the rise worldwide. Urinary tract infections as a result of Candida species are becoming common in hospitalized patients. The species identification of Candida is important, as non-albicans Candida species are increasing in number and more resistant to antifungal drugs. The present study was aimed to speciate, characterize and perform antifungal susceptibility testing of the yeast isolates from the urine samples. Material and methods: The study was conducted in the Department of Microbiology, Adesh Institute of Medical Sciences and Research, Bathinda over 1 year period. Atotal of 1732 urine samples were analysed and isolated Candida species were subjected to speciation and antifungal susceptibility was performed according to standard procedures. Results: A total of 100 Candida species were isolated from 1732 urine samples, incidence of candiduria was 5.77%. Candida tropicalis (C. tropicalis) was the commonest species (45%). Females in the age group >60 years (73%) were predominantly affected. Isolated species were more susceptible to Amphotericin (97%) and itraconazole (60%) followed by fluconazole (36%). Conclusion: Non-albicans Candida (NAC) species have emerged as important cause of urinary tract infections. Nonalbicans Candida (NAC) show is more resistant to antifungal drugs than Candida albicans (C.albicans). Therefore, the species identification of Candida isolates along with their antifungal susceptibility pattern can help the clinician in better treatment of patients with candiduria.
Authors and Affiliations
Ruchi Goel, Surinder Singh, Amarjit Kaur Gill, Amandeep Kaur, Ivneet Kour
Keywords
Related Articles
- EP ID EP430751
- DOI -
- Views 121
- Downloads 0
Rare Side Effects of Imatinib – Lichenoid Dermatitis - A Case Report
Introduction: The treatment for gastrointestinal stromal tumors remains surgery and small molecule tyrosine kinase inhibitor like imatinib. Case report: A 54 years adult male with Gastrointestinal stromal tumor (GIST) of...
Dermoscopy - A tool to Assess Stability in Vitiligo
Introduction: Vitiligo is defined as an autoimmune disorder of pigmentation characterised by loss of functional melanocytes and melanin in epidermis. Affects 0.3-1.1% of world population, irrespective of gender and race....
Palatal Schwannoma: A Rare Case Report
Introduction: Schwannomas are benign encapsulated perineural tumors. The head and neck region is the most common site. Intraoral origin is seen in only 1% of cases, tongue being the most common site; its location in the...
Impact of Obesity on Male Fertility in an Urban Nigerian Town
Introduction: Obesity is gradually becoming an epidemic disease that is rapidly spreading in both developed and developing countries. Recently it has been linked with fertility problems in men. The aim of this study is t...
Prevalence of ABO and Rhesus Blood Groups in Blood Donors: A Study from A Tertiary Care Centre in South Kerala
Introduction: The ABO and Rh blood group systems are the most important blood group systems in Transfusion Medicine. This study was carried out with an objective to study the distribution of ABO and Rh blood groups among...