Dermoscopy - A tool to Assess Stability in Vitiligo
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 10
Abstract
Introduction: Vitiligo is defined as an autoimmune disorder of pigmentation characterised by loss of functional melanocytes and melanin in epidermis. Affects 0.3-1.1% of world population, irrespective of gender and race. Study aimed at the morphological dermoscopic patterns and correlate with stability in vitiligo patients Material and Methods: White light dermoscopy is used in imaging patterns in 50 clinically diagnosed cases of Vitiligo which includes clinically stable vitiligo, unstable vitiligo, vitiligo cases on treatment during April 2016- June 2016 in our institution. Results: On examination with dermoscope, patterns like Marginal hyperpigmentation (40%), Reticulate pigmentation (38%), Perifollicular pigmentation (40%), Trichrome (32%), Starburst (16%), Comet tail (8%) were observed. In addition Erythema, Telangiectasia, Atrophy are also seen in patients on treatment. Marginal hyperpigmentation, Perifollicular pigmentation, Reticulate pigmentation are seen frequently in stable vitiligo patients. Trichrome, Starburst, Comet tail, Polkadot patterns are commonly seen in unstable vitiligo. Conclusion: Marginal hyperpigmentation, Reticulate pigmentation, Perifollicular pigmentation patterns suggest stability, Starburst, Comet-tail, Polkadot suggest unstability of disease. Patients with good response to treatment showed Marginal hyperpigmentation, Perifollicular and Reticulate pigmentation and poor response to treatment showed Trichrome, Starburst, Comet tail, Polkadot patterns on dermoscopy. Hence dermoscopy can be used to monitor the activity of disease, response to treatment and hence prognosis. Trichrome, Starburst, Comet tail, Polkadot patterns suggest change in treatment modality.
Authors and Affiliations
G. Purnima, N. A. Tejaswitha Gudivada, T. V. Narasimharao
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