Detection of Herpes Simplex Virus in Chronic Generalized Periodontitis via Polymerase chain Reaction –A Pilot Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: As bacterial etiology could not support and explain various aspects of periodontal disease, herpes virus is now proposed to be one of the causative factors responsible for the periodontal destruction. The purpose of present study is to detect the presence of Herpes simplex virus (HSV) in patients with chronic generalized periodontitis. Material and Methods: A total of 11 patients were consecutively selected for the study, out of which 3 were diagnosed with moderate chronic generalized periodontitis and 8 with severe chronic generalized periodontitis. Subgingival material was taken from the deepest pocket of the dentition from every study subject, before the commencement of any procedure and polymerase chain reaction(PCR) assay were done to detect the presence of HSV-1 and -2. Results: HSV-1 & -2 DNA was not detected in any of the samples. Conclusion: This study is in conflict with previous studies and questions the proposed pathogenic role and clinical relevance of herpes virus in periodontitis.
Authors and Affiliations
Thomas George V, Saumya John, Annu Elizabeth, Joseph, Bindiya Balram, Sreejith C K, Merry Mariyam Varghese
Keywords
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