Are antidepressants useful in bipolar disease?
Journal Title: Archives of Depression and Anxiety - Year 2017, Vol 3, Issue 2
Abstract
The treatment of bipolar depression is the subject of intensive research, as shown by the numerous references obtained only in the last year using the terms “bipolar depression and treatment” in MEDLINE. This is one of the signs of effervescence in the treatment of this affection leading to publication of consensus in North America and the United Kingdom which often don’t deal with clinical realities [1]. These publications systematically evaluate best practices, validate first choices and point out areas where there is not enough literature to produce best clinical practices [2]. The treatment of bipolar depression is certainly an area where a large number of randomized, double-blind studies and a strong evidence-based treatment algorithm produce data to refine our practices. But, although these results are endorsed by respected experts in the field, the detailed study of the references shows that most of these studies are carried out on limited samples, which are not very representative of our clinical population. However, the STAR-D study, funded by the NIMH, gives us very interesting data in the treatment of recurrent depressions [3]. These data are based on a large sample of relevant clinical population and recruited in multicenter sites.
Authors and Affiliations
Bourin Michel
Keywords
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- EP ID EP334496
- DOI 10.17352/2455-5460.000025
- Views 34
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