Articular cartilage regeneration in the treatment of osteoarthrosis
Journal Title: Kerala Journal of Orthopaedics - Year 2018, Vol 0, Issue 0
Abstract
Osteoarthrosis (OA), the most common joint disorder, produces a tremendous burden on healthcare systems throughout the world. Since there is no effective cure, OA represents a unique opportunity for innovation in the development of treatment strategy. In contrast to traditional treatments with drugs, proteins or anti bodies, stem cells are expected to revolutionize the treatment of many degenerative diseases including osteoarthrosis. There are ongoing debates whether stem cells can be effective in the treatment of complex diseases like osteoarthrosis. In this review the application of various methods for cartilage regeneration using stem cells in the treatment of osteoarthrosis is discussed. It is suggested that further investigations into new treatment strategies or combination therapies might provide useful treatment options in the management of osteoarthrosis. It is very important to evaluate the safety and effectiveness of cell based therapy before clinical use. This review provides updated information on recent clinical trials and related applications of stem cells in cartilage regeneration, there by opening up new treatment horizons in the management of osteoarthrosis.
Authors and Affiliations
P S John P S John, Varghese Thomas
Keywords
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