Assessing The Glycemic Control in Type 2 Diabetic Patients By Comparing Glycosylated Hemoglobin Levels (Hba1c) With Fasting And Postprandial Glucose
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 1
Abstract
Background: Diabetes Mellitus (DM) is a metabolic disorder characterized by the presence of chronic hyperglycemia accompanied by greater or lesser impairment in the metabolism of carbohydrates, lipids and proteins resulting from insulin resistance, and relative insulin deficiency. Objectives: This study was conducted to assess the correlation of glycosylated hemoglobin levels with fasting and postprandial glucose in type 2 diabetic patients attending Mahavir institute of Medical Sciences (MIMS) – hospital, (Central Laboratory) Vikarabad, Telangana State, India. Method: A Retrospective observational study was undertaken at MIMS after obtaining clearance from the Institutional Ethical Committee. A simple random sampling technique was adopted, over a period of six months. Data was collected on the Subjects attended the different In-patient departments of MIMS, diagnosed with type 2 diabetes mellitus (T2DM), that fasting blood sugar (FBS), postprandial blood sugar (PPBS) and HbA1c measured during previous follow-ups were included in the study. The study population was divided into two groups based on the HbA1c values i.e. Group 1 Controlled (<6.55) Group 2 Uncontrolled ( 6.56 >7.9). Result: Both postprandial blood glucose and fasting blood glucose significantly correlated with HbA1c. Postprandial blood glucose showed better correlation to HbA1c than fasting blood glucose (r= 0.33, P=0.001* vs r=0.206 P=0.04*). Conclusion: These results show that postprandial blood glucose predicted overall glycemic control better than fasting blood glucose. In conditions with limitations for using HbA1c, FBS & PPBS can be used to monitor the glyceic control.
Authors and Affiliations
Gulam Saidunnisa Begum, Ayesha Jabeen, Amtul Rahman
Keywords
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- EP ID EP415002
- DOI 10.9790/264X-04015457.
- Views 172
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