ASSESSMENT OF ANTIFUNGAL ACTIVITY OF CASSIA FISTULA L. FRUIT PULP AGAINST ALTERNARIA SOLANI
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
In the present study antifungal activity of crude and partially purified extracts of Cassia fistula L. fruit pulp has been assayed against Alternaria solani which is responsible for early blight of potato. Cold and hot extracts of fruit pulp was prepared in different organic solvents, which were subsequently recycled by rotary vacuum evaporator. Antifungal activity of different fractions was determined by poison food technique. Maximum percent extractive value was obtained with alcoholic extract. Maximum inhibitory activity was observed with 100% alcohol crude extract and partially purified chloroform extract against Alternaria solani. Mancozeb and bavistin were used as standards. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of chloroform fraction of Cassia fistula fruit pulp was investigated against Alternaria solani. Results suggest that Cassia fistula L. fruit pulp extract can be used to develop a biocontrol agent against Alternaria solani. The antifungal activity of the Cassia fistula was due to the presence of various secondary metabolites. Hence, this plant can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.
Authors and Affiliations
Deepa Hada, Kanika Sharma
Keywords
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