Assessment of atherosclerotic lesions in coronary arteries using a modified SYNTAX score in patients with diabetes and acute coronary syndrome treated with coronary angioplasty and the prognosis
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 3
Abstract
<b>Introduction and aim.</b> An angiographic score assessing atherosclerotic lesions in coronary arteries, capturing number of lesions, their character, localization, functional influence and complexity may be a useful tool prognosing future cardiovascular episodes during short- and long-term observation of patients with diabetes treated by coronary angioplasty.<br><b>Material and methods.</b> A hospital database was analyzed in order to collect data in the years 2000-2005. From all patients with acute coronary syndrome (2664) hospitalized in tat time 233 (8.7%) were selected. Atherosclerotic lesions in coronary arteries were assessed using a modified SYNTAX score (SS). Demographic data: mean age 79.03 ± 3.44, proportion of males 131 (56.2%), STEMI 123 (52.7%), hypertension: 193 (82.8%), chronic kidney disease: 59 (25.3%), stroke: 21 (9%), dyslipidaemia: 181 (77.8%), smokers: 76 (32.6%), EF: 46.8 ± 10.7%, mean SYNTAX score: 23.15 ± 12.3. The patients were divided according to the presence of diabetes: with (114, 48.9%) or without this disease.<br><b>Results.</b> Diabetics are characterized by more advanced atherosclerotic lesions in comparison with those without diabetes (SYNTAX score: 28.5 ± 13.6 vs. 18.1 ± 8.1; p = 0.0001), especially when localized near big vessels (69.3% vs. 55.5%; p = 0.029). In a Cox proportional hazard regression it was shown that increase of the risk of early complications was associated with diabetes (HR 1.7; p = 0.04), coronary artery amputation (HR 4, p = 0.03) and higher SYNTAX score (HR 1.01; p = 0.049), increased risk of intrahospital complications was associated with higher SYNTAX score (HR 1.027; p = 0.01), and long-term prognosis was associated with the presence of coronary artery amputation (HR 4.19; p = 0.01).<br><b>Conclusions.</b> More advanced atherosclerotic lesions in coronary arteries in patients with acute coronary syndrome is associated with worse prognosis in short- and long-term observation.
Authors and Affiliations
Bernadetta Kałuża, Piotr Seweryniak, Tomasz Kulawik, Robert Gil, Edward Franek
Keywords
Related Articles
- EP ID EP54677
- DOI -
- Views 92
- Downloads 0
Renal function in patients with pacemaker and diabetes
Gene therapy of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder affecting nearly half a million people worldwide. Approximately 35% of familial and 10% of sporadic cases are due to mutations in genes encoding f...
Vascular complications after cardiac invasive procedures – diagnosis and management
Arterial puncture is related with the risk of bleeding and site complications. Therefore this procedure should be performed by physicians. Vascular complications present an important problem in contemporary invasive card...
Rak żołądka
Wyniki leczenia raka żołądka są niezadowalające. Zwiększenie zakresu limfadenektomii nie prowadzi do poprawy wyników. Poprawy wyników leczenia poszukuje się w leczeniu okołooperacyjnym, tj. kojarzeniu leczenia chirurgicz...
Ocena stężenia białka C-reaktywnego, interleukiny 6 i jej rozpuszczalnego receptora w surowicy dzieci z niealkoholową chorobą stłuszczeniową wątroby
<b> Wstęp.</b>Niealkoholowa choroba stłuszczeniowa wątroby (NAFLD) jest uważana za schorzenie charakteryzujące się obecnością przewlekłego ogólnoustrojowego procesu zapalnego o niewielkim nasi...