Assessment of Platelet Count in Normal Kashmiri Population
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Macrothrombocytopenia, a combination of thrombocytopenia and giant platelets, can occur in a number of diseases, including chronic immune thrombocytopenia purpura and inherited giant platelet disorders. It is present in at least 12 inherited syndromes as well as in some acquired immunemediated and hematological disorders. Study aimed to evaluate the platelet count in normal Kashmiri population,using hematology analyser sysmex XT-2000i in comparison with manual platelet counting(Neubauer chamber) recommended by the international committee for standardization in Hematology. Material and Methods: In present study, 500 samples of blood were collected from apparently Normal kashmiri Population and were processed by automated analyzer (Sysmex XT-2000i) and Manual Platelet Counting (Neubauer chamber). Multiple comparisons were done between the Automated and Manual method. Results: The result demonstrated variation in platelet count between automated analyzer and Manual Platelet Counting.The mean value of platelet count estimated by automated analyzer was found to be 126.40 x 103/μl (Range: 47.0-394.0 x 103/μl) while the mean value of platelet count estimated by manual method was 139.06 x 103/μl (Range: 60.0-390.0 x 103/μl) and was found to be statistically significant (p<0.0001).Similarly, the mean value of platelet count estimated by automated analyzer in males and females was found to be 125.64 x 103/μl (Range: 47-394 x 103/μl) and 152.93 x 103/μl (Range: 84-223 x 103/μ) respectively. During analysis it was found that platelet count by manual method is higher as compared to the automated method in our laboratory. Conclusion: The study highlights the differences in platelet count in our population using automated and manual method. Higher platelet count by manual method in our population may be because of large platelet size which analyzer’s are not able to count and therefore the results should be carefully interpreted
Authors and Affiliations
Sajad Geelani, Tazeen Jeelani, Sanam Altaf, Mudasir Qadri, Ashaq Altaf, Nusrat Bashir, Fahim Manzoor, Shuaeb Bhat, Javid Rasool, Samoon Jeelani
Keywords
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