Salivary Glucose Level and its Correlation With Blood Glucose Level in Patients with Diabetes Mellitus-an in-Vivo Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 12
Abstract
Introduction: Diabetes mellitus is a globally widespread metabolic disease caused due to hyperglycemia, which is the result of defect in insulin secretion, insulin action, or both. The aim of the study was to assess the correlation of fasting blood glucose level (FBG) and fasting salivary glucose level (FSG) in diabetic and non-diabetic patients. Material and methods: An experimental study was conducted in 60 patients who fulfilled the selection criteria. Patients were categorized into 2 groups -30 patients with diabetes mellitus (Group A) and 30 healthy non-diabetic patients (Group B). The fasting blood and unstimulated saliva samples were collected from the patients. These samples were then subjected for analysis of glucose in blood and saliva using HEXOKINASE reagent in Abbot C4000 Automatic analyzer and the results were recorded. Results: A statistically significant difference (p=0.0001*) was found between the fasting blood glucose level between the 2 groups with mean FBG level in group A (182.23±12.67) and fasting blood glucose level among group B was 73.59±7.56. The mean FSG was higher in diabetic group (13.13± 3.2) than in non-diabetic group (0.72±0.08). A highly statistically significant correlation was found between fasting salivary glucose and fasting blood glucose in both the groups. Conclusion: The present study clearly depicts that fasting salivary glucose is increased in diabetics and this finding was statistically significant. On the basis of the findings, it was concluded that salivary glucose levels could serve as a potentially noninvasive adjunct to monitor glycemic control in diabetic patients
Authors and Affiliations
Afreen Nadaf, Zhahid Hassan, Summiya Farooq
Keywords
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