Assessment of Serum Electrolytes & Uric Acid Level in Hypothyroid Patients in Western Uttar Pradesh.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction: Thyroid hormone is a central regulator of body functions. Disorders of thyroid function are considered to be a cause of electrolyte alterations. Only few data on the association between thyroid function and electrolyte disorders exist. Aim of the study was to find out the association between serum sodium, potassium and uric acid level with fT3, fT4&TSH in hypothyroid patients.Materials&Methods: Total 70 newly diagnosedhypothyroid patients were included in the study. Sera were collected from them and serum sodium, potassium, uric acid, fT3, fT4&TSH level were estimated in thestudy group. Result: Patients with hypothyroidism showed significant decrease in serum sodium level and significant increase in serum potassium and uric acid level (p<0.05).When correlated with TSH level, the correlation was negative for sodiumwhereas positive for the potassium and uric acid. Correlation with fT3 and fT4 level was positive with sodium and negative with potassium and uric acid level.Conclusion: The present studyindicates the profound influence of thyroid hormones on serum uric acid and electrolytes. We suggest that hypothyroid patients should be regularly monitored for serum electrolytes and uric acid level. Monitoring of these parameters inhypothyroidism will be of great help in the management of the patients.
Authors and Affiliations
Rashmi Sinha, Indu Bhushan
Keywords
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