Assessment of Serum Vitamin D Level in Asthmatic Patients
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 4
Abstract
Aim: Asthma is a clinical condition which causes constriction in airway with shortness of breath, chest tightness, cough and wheeze. It can be mild, moderate and severe. Vitamin D is obtained directly from sunlight and through the diet. It is a fat-soluble natural nutrient which is a modulator of calcium absorption and bone health. It also plays an important role in immune regulation and in respiratory infections. Materials & Methods: This study was conducted in the department of Biochemistry, People’s College of Medical Science & Research Centre Bhopal (M.P.). For the study purpose 100 cases and 100 controls were selected randomly and perform Vitamin D test by CLIA method (kit method) in the laboratory. This study was based on comparison of serum vitamin D level of cases and controls. Compare serum vitamin D level according to the age groups of patients and according to duration of asthma and found the level of significance. Results: Serum vitamin D level is found to be lower in asthmatic patients than controls. There were no significant result found among the different age groups of asthmatic patients and groups of duration of asthma. Conclusion: Vitamin D plays a significant role in inborn and adaptive immunity but still it is under discussion. The discovery of vitamin D receptor (VDR) connected vitamin D to the immune system. Several researches suggested an autoimmune role of vitamin D due to its effects on immune cells such as T lymphocytes, B lymphocytes, and dendritic cells.
Authors and Affiliations
Pallavi Mishra, Dr. Prashant Hisalkar, Dr. Neerja Mallik, Dr. Anupama Patane
Keywords
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- EP ID EP415130
- DOI 10.9790/264X-0404016871.
- Views 139
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