Abstract

Thymus vulgaris is a species of Lamiaceae family which possess a number of pharmacological properties, like anti-oxidative, antiseptic, antimicrobial, antispasmodic, antitussive, antifungal, antiviral anti-inflammatory. In this study, two type of formulation loaded with thyme hydro alcoholic extract, thyme aqueous extract, rosmarinic acid and rutin respectively were studied by the means of non-invasive methods on human healthy volunteers. Skin parameters’ change, in terms of trans epidermal water loss, erythema and the moisture of corneous layer, was evaluated after the application of the test compounds. The assessment of formulations suggest that these products are safe to use in skin preparation. Low changes of erythema, trans-epidermal water loss and skin moisture were observed in the case of samples based on rosmarinic acid, respectively thyme extract.

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