Assessment of Vitamin D and its Correlation with Lipid Markers among Adult Female during the Course of Pregnancy in and Around Dhanbad, Jharkhand
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 6
Abstract
Introduction: Vitamin D deficiency is one of the common health issue and is widespread throughout the world. It’s dietary supplementation is generally advised in the general population, including pregnant women. However, data about the relation between vitamin D status and the lipid profile in adult females during pregnancy is inconsistent. The present study was designed with the aim to assess the status of vitamin D and its relationship with the serum lipid profile in the females during pregnancy in and around Dhanbad Jharkhand. Material and Methods: A total of 110 females were recruited for this study out of which 55 were taken as control and 55 as cases. An informed consent was taken from each patient. Chemiluminescent microparticle immunoassay (CMIA) was used with automated instrument for estimation of 25-hydroxyvitamin D. Lipid profiles were assessed using standard procedures. Result: In the study, vitamin D deficiency was noted in the case group in 61% females whereas 39% females had values within normal limits. A statistically significant inverse correlation was found between 25 hydroxyvitamin D levels and TC, VLDL, LDL and TG levels in pregnancy. Conclusion: The status of Vitamin D was found to be less in the pregnant females as compared to in healthy and nonpregnant females. Also, the result showed that the serum 25(OH)D and lipids levels are related to each other. It seems that vitamin D deficiency may be associated with the increased risk of dyslipidemia.
Authors and Affiliations
Krishna Kumari, Rajendra Kumar, Siyavar Sharan
Keywords
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