Association between Periodontitis and Cardiovascular Diseases: A Clinicobiochemical Study
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2014, Vol 11, Issue 1
Abstract
Introduction: The periodontal tissues mount an immune inflammatory response to bacteria and their products and the systemic challenge with these agents also induce a major vascular response. Oral infection models have emerged as useful tools to study the hypothesis that infection is a cardiovascular disease (CVD) risk factor. Periodontal infections are a leading culprit, with studies reporting associations between periodontal disease and CVD. Material and Methods: The study was conducted on a group of 50 individuals aged 30 to 65 years, divided in five different groups depending on the type of cardiovascular disease diagnosed. These five groups were: Ischemic heart disease, bacterial endocarditis, Congestive cardiac failure, valvular heart disease and cardiomyopathies. The dental investigations comprised of Ramjford’s periodontal disease severity index and clinical attachment level Laboratory investigations were done for lipid profile analysis. Observations and Results: Ramjford’s disease severity index showed a significant difference (p<0.05) between Bacterial endocarditis and Valvular heart disease. This index also showed significant positive correlation with total cholesterol, triglycerides and VLDL and showed negative correlation with HDL. Attachment level was not significant between Valvular heart disease and Cardiomyopathies. However, it showed positive correlation with total cholesterol. Lipid profile showed dyslipidaemia with Ischemic Heart Disease. Conclusion: The study concludes that Bacterial endocarditis and Ischemic heart diseases have severe degree of periodontitis as compared to Valvular heart diseases, cardiomyopathies and congestive cardiac failure.
Authors and Affiliations
Kalpana U. Rakshit , Neelima Rajhans , Pankaj Kamble , Nilkanth Mhaske , Reader , Senior Lecturer
Keywords
Related Articles
- EP ID EP147231
- DOI -
- Views 83
- Downloads 0
Complete Simple Syndactyly
Syndactyly is the most common congenital malformation of the limbs, with a large aesthetic and functional significance. Syndactyly is a failure of differentiation in which the fingers fail to separate into individual ap...
The effect of levothyroxine substitution on lipid profile parameters in patients of subclinical hypothyroidism in tertiary care centre of kumaon region
Introduction- Subclinical hypothyroidism (SCH) also called as mild thyroid failure is defined as the presence of serum thyroid stimulating hormone (TSH) above the statistically defined upper limit of the reference range,...
Study of Serum Ferritin Levels in Anemia of Pregnancy
Anemia in pregnancy is a global problem and is associated with increased maternal morbidity and mortality (WHO, 1992). Iron deficiency anemia is defined as anemia accompanied by depleted iron stores and signs of a compro...
To Study the Chemotherapeutic Effect of Doxorubicin When Combined With Aspirin and Clopidogrel in Ehrlich Ascites Carcinoma Induced Adult Wistar Rats
Objective: To determine whether there is an enhanced chemotherapeutic effect of Doxorubicin when combined with Aspirin and Clopidogrel (anti platelet drugs) in Ehrlich Ascites Carcinoma induced adult wistar rats.Methodol...
A study of clinical profile and complications of Poisonous snake bites in a tertiary care hospital in south India
Background: Snake bite is still a major public health hazard which is preventable and treatable. The clinical features of snake bite envenomation are highly varied. Aims: To study the clinical profile and complications o...