Association of Cord Blood Neutrophil Levels with Early Onset Sepsis in Very and Moderate Preterm Infants
Journal Title: Hippocrates Medical Journal - Year 2022, Vol 2, Issue 2
Abstract
Introduction It was aimed to determine the relationship between cord blood neutrophil values and early onset neonatal sepsis (ENS) and ENS risk factors in very and moderate preterm infants. Methods In our retrospective study, the cases who were born between 28-34 weeks of gestation and hospitalized for at least seven days were evaluated. Blood counts obtained from umbilical cord or in the first two hours of life, blood culture results, CRP values, risk factors for ENS, and clinical features were recorded. Results The mean birth weight and gestational age of patients (n=100) were 1617±408 grams, and 32.19±1.6 weeks, respectively. In the 33 of the cases the cord blood, and in the 67 of the cases venous neutrophil counts taken within the first two hours after delivery were evaluated. There was no difference between cord and venous blood neutrophil values (p= 0.936). There was no difference in terms of neutrophil values between those with/without ENS and with/without ENS risk factors (p = 0.076, 0.95, respectively). Neutrophil levels were positively correlated with gestational week and birth weight, and negatively correlated with CRP values (r, p = 0.282, 0.004; 0.437, 0.0001; -0.209, 0.037, respectively). Conclusion No relationship was found between cord blood/ venous blood neutrophil levels and ENS/ ENS risk factors. Our findings suggest that neutrophil values should be evaluated by considering gestational age and birth weight in preterm infants.
Authors and Affiliations
Asli OKBAY GÜNEŞ, Sevilay TOPÇUOĞLU, Nilgün KARADAĞ, Elif ÖZALKAYA, Güner KARATEKİN
Keywords
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- EP ID EP708995
- DOI https://doi.org/10.29228/HMJ.13
- Views 78
- Downloads 0
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