Association of serum calcium level with metabolic syndrome: A case-control study
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 7, Issue 3
Abstract
Background: Metabolic Syndrome (MetS) is highly prevalent in urban India. Circulating calcium has direct association with vascular disease like cardiovascular disease Calcium play crucial role in proper function of the insulin and lipid metabolism. Objectives: To assess serum calcium level in MetS patients and it association with parameters of the MetS Materials and Methods: It was a hospital based case control study. A total of 50 MetS cases and 50 age-matched healthy controls were included in the study. Cases were selected according to revised IDF criteria for MetS. Estimation of serum calcium, fasting blood sugar, triglyceride and HDL were done on advia 1800 chemistry autoanalyzer. Results: Serum calcium was found higher in MetS patients compared to controls. Mean ± SD value of serum calcium among cases and controls were 10.1 ±0.85 and 9.3 ± 0.62 mg/dl respectively (P<0.0001).We found significant association of calcium with FBS and serum triglyceride level with calcium. Both FBS (P=0.01) and triglyceride level (P=0.02) increased linearly with increases in calcium. There was no significant association of waist circumference, serum HDL and blood pressure with serum calcium level. Conclusion: Serum calcium level was high in metabolic syndrome cases compared to controls. Serum calcium has significant association with fasting blood sugar and triglyceride level.
Authors and Affiliations
Sagar Dholariya, Prashant K Nichat, Leela G Abichandani
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