Modified method for partial purification of human blood clotting factor VIII from fresh frozen plasma
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 3, Issue 3
Abstract
Human blood is an irreplaceable commodity. Its proteinaceous structure, the compatibility and others. Factor VIII to the haemophilic patient provides need to make available Clotting Factor VIII from freeze dried fresh plasma with Factor VIII of coagulation has longer shelf life (2 years) and can be introduced to the patient with less interference of immunological complications. The present study established cryoprecipitate - rich in Coagulation Factor VIII without significant loss of activity. The gradual treatment of change in temperature followed by lyophilisation produced enriched fraction. Thus the Coagulation Factor for infusion to the required haemophilic patient readily.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP258565
- DOI -
- Views 282
- Downloads 0
A study of renal function in the hypothyroid patients at the tertiary health centre
Background: Thyroid diseases are the most common endocrine disorders world-wide. India too is no exception. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million p...
Comparative assessment of oxidative stress and enzymatic antioxidants in primigravidae pregnant and non-pregnant women
Background: The generation of reactive oxygen species and the activation of antioxidant defence mechanisms are important components of female reproductive physiology. It's impairment alters cellular signalling and can da...
25(OH) vitamin D level and severity of chronic liver disease: A controlled study from Eastern India
Background: Chronic Liver Disease (CLD) is defined as long term process of progressive degeneration and regeneration of liver cells and with advancement, leads to hepatic fibrosis, scarring, and cirrhosis. 25(OH) Vitamin...
Regulatory role of HDL on systemic inflammatory response in adult bacterial sepsis
Background: Inspite of the recent advances available in the intensive care units (ICU) there is still an increasing incidence of sepsis and sepsis related deaths. Recent studies suggest that high density lipoprotein (HDL...
Creatinine estimation by compensated Jaffe method and enzymatic method - A comparative study
Background: Chronic Kidney Disease is a global threat to health particularly for developing countries, since therapy is expensive and life-long. Incidence of CKD has doubled in the last 15 years. Accurate creatinine meas...