A study of renal function in the hypothyroid patients at the tertiary health centre
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 1
Abstract
Background: Thyroid diseases are the most common endocrine disorders world-wide. India too is no exception. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid diseases. Aims and Objective: To study Renal function in the Hypothyroid patients at the tertiary health Centre. Methodology: After approval from institutional ethical committee this cross- sectional study was carried out in the patients of the hypothyroidism at Viswabharathi Medical College and Hospital during the year January 2016 to December 2016. The diagnosed patients of hypothyroidism who gave consent were enrolled into the study and similar eu-thyroid patients also included into the study. The renal function test with parameters like Creatinine Clearance, Creatinine Urea, Uric acid etc. was done in both the groups. The statistical analysis done by unpaired t test calculated by SPSS 19 version software. Result: The majority of the patients were in the age group of 30-39 i.e. 48%, followed by 40- 49 -16%, 50-59-12%, >60-10%.The majority of the patients were Female i.e. 66% followed by Male 24%. Creatinine Clearance was significantly lower i.e. 102.04±9.99 80.72±10.58 (P<0.001), Creatinine -0.86±0.101, 0.728±0.0453 (P<0.001); Urea -28.14±3.14, 21.86±3.05(P<0.001); Uric acid-5.086±0.7617, 3.122±0.159(P<0.001) significantly higher in the hypothyroid patients as compared to control.Conclusion: It can be concluded from our study that the majority of the hypothyroid patients were female and in the age group of 30-39, the hypothyroid patients shown significantly deranged renal function test in the form i.e. Creatinine Clearance was significantly lower Creatinine, Urea, Uric acid,significantly higher in the hypothyroid patients as compared to euthyroid.
Authors and Affiliations
Swapna V S, Vani B, Dinesh Javerappa
Keywords
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