Autologous Platelet-Rich Plasma In Diabetic Foot Ulcers, New Preparation Technique
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 10
Abstract
Aim of work: To assess the healing of diabetic foot ulcers attributed to newly technique preparation of platelet-rich plasma (PRP) compared with that in the control group with conventional procedures. Methods: A prospective study was carried out between January 2016 to July 2017 on 80 patients suffered from chronic diabetic foot ulcer not responding to the traditional treatment. Patients were classified into 2 groups:- group A; included 42 patients that were treated by application of autologous PRP prepared by minimal cost technique and group B; including 38 patients that were treated with the traditional methods of ulcer management. Results: Mean ulcer area and ulcer volume in group (A) before treatment were 15.7 cm2 and 14.1 cm3 respectively while in group (B) were 16.49 cm2 and 14.01 cm3 respectively. Healing rate was (83.33%) in 35 patients in group (A) and (28.95%) in 11 patients in group (B). No patients suffered from any undesired effects that were directly related to PRP treatment apart from minimal skin irritation around the ulcer if the dressing was infrequently changed. Conclusion: Autologous platelet-rich plasma combined with conventional treatment methods accelerates healing process of diabetic foot ulcers. Easily prepared PRP is safe and cost-effective with reasonable results.
Authors and Affiliations
Osama A. Ismail
Keywords
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- EP ID EP549410
- DOI 10.22192/ijcrms.2018.04.10.009
- Views 144
- Downloads 0
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