BACTERIOLOGICAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY PATTERN OF BLOOD CULTURE ISOLATES FROM BURN PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 83
Abstract
BACKGROUND Infection in a burn patient is a leading cause of morbidity and mortality and remains one of the most challenging concerns for doctors. The aim of this study is to determine the bacteriological profile of blood stream infections and their antibiotic sensitivity pattern. MATERIALS AND METHODS One hundred sixteen blood samples were collected from acutely burnt patients, being treated in the Rajendra Surgical Ward of the Patna Medical College and Hospital, Patna. This descriptive study was conducted from July 2004 to August 2005. RESULTS In the present series of study, it is observed that out of a total of 17 isolates (5.84%) of Staphylococcus aureus, 14 isolates (i.e. 82.35%) were sensitive to Cloxacillin. Antibiotics resistant to Staphylococcus aureus were Gentamicin, Amikacin, Cotrimoxazole, Lomefloxacin, out of a total of 27 (i.e. 9.28%) isolates of Pseudomonas aeruginosa, 11 isolates (i.e. 40.74%) were sensitive to Gentamicin and 13 isolates (i.e. 48.15%) were sensitive to Imipenem. Isolates were resistant to Cloxacillin, Ampicillin, Cefazolin and Cotrimoxazole. Out of a total of 7 isolates (i.e. 2.41 %) of Proteus spp., 6 isolates (i.e. 85.71%) were sensitive to Imipenem. Isolates were resistant to Cloxacillin, Cefazolin, Cefoperazone. Out of a total of 6 isolates (i.e. 2.06 %) of Klebsiella spp., 3 isolates i.e. 50% were sensitive to Imipenem and 2 isolates (i.e. 33.3 %) were sensitive to Imipenem. Isolates were resistant to Ampicillin, Cloxacillin, Cefazolin. Out of total of 4 isolates (1.37%) of E. coli, 3 isolates (i.e. 75%) were sensitive to Imipenem. Isolates were resistant to Ampicillin, Lomefloxacin and Cloxacillin. Proteus spp. are becoming difficult because of the development of resistance to newer antibiotics. So, inadvertent use of antibiotics must be discouraged. CONCLUSION In spite of use of effective antimicrobial agents, the problem of control of infection in burn patients still persists. Pseudomonas aeruginosa is still the major pathogen responsible for bacteraemia in burn wound infection. Other important bacteria are Staphylococcus aureus and Proteus spp. Pseudomonas aeruginosa is sensitive to Imipenem and ciprofloxacin; Proteus spp. to Ceftriaxone; Staphylococcus aureus to cloxacillin; E. coli to ciprofloxacin and Cefotaxime; Klebsiella spp. to ciprofloxacin and gentamicin; Streptococcus pyogenes to cefotaxime and cefoperazone; and Staphylococcus epidermidis to cloxacillin.
Authors and Affiliations
Rajpal Kamlesh, Kumar Ajay, Nag Sanjay, Lal Arjun, Mahto S. P
Keywords
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- EP ID EP276123
- DOI 10.14260/jemds/2017/1261
- Views 87
- Downloads 0
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