BACTERIOLOGICAL PROFILE AND THE ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ENDOTRACHEAL SECRETIONS IN ICU OF A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 18
Abstract
BACKGROUND Patients on mechanical ventilation are at higher risk of acquiring hospital acquired infection due to interplay of compromised host defense, virulent organism and presence of invasive device. Knowledge of local bacteriological trend of the antibiotic susceptibility pattern is a must to initiate a judicious antibiotic treatment. MATERIALS AND METHODS The study was a retrospective descriptive study analysis of endotracheal (ET) samples of patients on mechanical ventilation done over a period of 6 months from July 2017 to Dec 2017. This was done to analyse bacteriological profile and their antibiotic susceptibility. RESULTS 44 out of 82 samples showed growth accounting for total of 53% (positive cultures). Gram negative bacteria were the most common isolates with Klebsiella spp. being the most common bacteria followed by Pseudomonas aeruginosa. Acinetobacter baumannii, though the most resistant organism was a rare isolate. Klebsiella was the most common as well as an MDR (multidrug resistant) isolate. CONCLUSION Gram negative bacteria are the major isolates from ET secretions of patients on mechanical ventilation in our ICU setup, Klebsiella being the most common and resistant too. An antibiogram specific for healthcare setting is a must that shall be based on bacteriological profile and organism’s sensitivity pattern.
Authors and Affiliations
Pooja Gupta, Shilpa Gupta, Jung Bahadur Singh
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