A COMPARATIVE STUDY OF INSULIN RESISTANCE IN OFFSPRINGS OF TYPE 2 DIABETES MELLITUS AND NON DIABETIC PATIENTS, A ONE YEAR CROSS SECTIONAL HOSPITAL BASED STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 41
Abstract
To assess the insulin resistance in offspring’s of type 2 diabetes mellitus patients, with off springs of non-diabetic patients. [b]METHODOLOGY[/b]: The study included offspring’s of 30 diabetic and 30 non-diabetic patients with a proper clinical examination according to predesigned and pretested proforma. Mean age, insulin levels, Homeostasis model assessment-insulin resistance (HOMA-IR) and BMI of the two groups were compared using unpaired‘t’ test. Chi – square test and Kruskal Wallis test were used to test the association between two or more variables in case of frequency distribution. [b]RESULTS[/b]: It was observed that the offspring’s in case group had higher insulin levels compared to control group. Insulin resistance was found to be 48.5% in case group and 19.4% in control group which was considered is statistically significant (p=0.009). Insulin resistance was seen in 47.05% offspring’s whose fathers were a diabetic, 41.6% offspring’s whose mother were a diabetic and 66.6% offspring’s had history of both parents being diabetic. However, the p value was not statistically significant (p=0.597).
Authors and Affiliations
Arathi Darshan, Vikas Patil , Yeshvant G
Keywords
Related Articles
- EP ID EP101105
- DOI 10.14260/jemds/1381
- Views 69
- Downloads 0
A CLINICOPATHOLOGICAL STUDY OF TUMOURS AND TUMOUR-LIKE LESIONS OF THE STOMACH
BACKGROUND Gastric cancer is the second most cancer worldwide after lung cancer despite a global decline in its incidence. 1 In most countries, the annual incidence of new cases of gastric cancer ranges between...
THE PATTERN OF BACTERIAL PATHOGENS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PROFILE FROM LOWER RESPIRATORY TRACT SPECIMENS IN A RURAL TERTIARY CARE CENTRE
BACKGROUND Lower Respiratory Tract Infections (LRTIs) is one of the leading infective health problems worldwide. The inappropriate use of antibiotics for these infections has led to a dramatic increase in antibi...
STAPHYLOCOCCUS AUREUS- HOSPITAL ACQUIRED AND COMMUNITY ACQUIRED, AND ANTIMICROBIAL TESTING IN A TERTIARY CARE HOSPITAL
BACKGROUND Staphylococcus aureus is a major pathogen causing a diversity of infections including bacteraemia, pneumonia, skin and soft tissue and osteoarticular infections. Infections due to MRSA are associated with incr...
ANALYSIS OF SUPRACUTANEOUS LOCKING COMPRESSION PLATE IN COMPOUND DISTAL METAPHYSEAL FRACTURES OF TIBIA- A PROSPECTIVE STUDY
BACKGROUND Complexity of open tibial fractures is on the rise with increased high-velocity road accidents. Temporary bony stabilization by external fixation avoids the instability at the fracture site and promotes healin...
A COMPARATIVE STUDY OF CARDIOVASCULAR STABILITY IN UNILATERAL AND BILATERAL SPINAL BLOCK IN LOWER LIMB SURGERY (FRACTURE TIBIA)
BACKGROUND Spinal anaesthesia is an effective alternative to general anaesthesia when the surgical site is located on the lower extremities, perineum or lower body wall. It is easy to perform and results in sympathetic b...