NEONATAL SEPSIS- ORGANISMS RESPONSIBLE AS DETECTED BY BLOOD CULTURE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 58
Abstract
BACKGROUND Neonatal sepsis refers to bacteraemia and clinical symptoms of infection caused by microorganisms and their toxic products in the first four weeks of life. It is the major cause of mortality and morbidity in neonates and accounts for 30% - 50% of neonatal deaths in developing countries. In India incidence reported as 30 per 1000 live births for the year 2002 - 2003. Blood culture is the gold standard for diagnosis of neonatal sepsis apart from utility of routine haematological, biochemical and radiological tests. Now BacT/ALERT 3D microbial detection system are being used for blood culture. This study will enable us to have important data regarding bacteriological spectrum associated with neonatal sepsis in suspected sepsis cases admitted in our rural hospital in Bihar. MATERIALS AND METHODS Our study included suspected cases of sepsis among all neonates delivered at this hospital and also included cases of neonatal sepsis referred from outside. We included 341 cases of neonates, which were suspected to have sepsis and in whom blood cultures were done. RESULTS Out of total 341 cases of suspected sepsis, 146 (42.8%) showed positive isolates confirmed by blood culture. We had total 62 (42.3%) Gram positive, 70 (48.1%) Gram negative and 14 (9.6%) fungal isolates out of total 146 positive blood culture isolates. CONCLUSION Our study showed that gram negative bacteria was the predominant cause of infection among neonates in our hospital. Coagulase negative Staphylococcus and Klebsiella were commonly isolated organisms among outborn and inborn neonates respectively
Authors and Affiliations
Shyamali Datta, Panchanan Ghosh
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