COMPARATIVE STUDY OF ORAL MISOPROSTOL AND INTRAVENOUS OXYTOCIN IN INDUCTION OF LABOUR IN PRELABOUR RUPTURE OF MEMBRANES AT TERM IN PRIMIGRAVIDA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2016, Vol 5, Issue 67
Abstract
BACKGROUND Prelabour Rupture of Membranes (PROM) is a common complication of pregnancy that has a major impact on maternal and neonatal health. Induction of labour may help in reducing infectious morbidity. AIM To compare the efficacy of oral misoprostol and intravenous oxytocin in induction of labour in prelabour rupture of membranes at term in primigravida. STUDY DESIGN Total of 100 primigravida patients with term PROM were chosen and divided into two groups. Labour induction done with either oral misoprostol or intravenous oxytocin. MATERIAL AND METHODS 50 women received 100 mcg of oral misoprostol every 6 hrs. for a maximum of two doses. The other 50 women received intravenous oxytocin 2.5 units in 500 mL ringer lactate as an infusion. The induction delivery time, mode of delivery, Apgar scores, and third stage losses noted. RESULTS The mean induction delivery interval (8.3 hrs.) in oral misoprostol group is similar to intravenous oxytocin group (8.4 hrs.). Mode of delivery is also similar in both groups. Uterine tachysystole and hypertonus did not occur in both groups. In oral misoprostol, there was the incidence of systemic side effects. CONCLUSION Oral misoprostol offers an alternative treatment in induction of labour in term PROM. Oral misoprostol 100 mcg is similar to intravenous oxytocin in efficacy in such cases. Neonatal outcomes are not affected. Its cost effective and easy to administer. Can be stored at room temperature.
Authors and Affiliations
Thangathai , Kasthuri
Keywords
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- EP ID EP164880
- DOI 10.14260/jemds/2016/1100
- Views 60
- Downloads 0
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