Bacteriophage therapy for treating multiple-drug resistant urinary tract pathogen, Escherichia coli
Journal Title: International Journal of Life Science - Year 2018, Vol 6, Issue 2
Abstract
The aim of the study is to prove the efficacy of phage therapy for treating multi drug Resistant (MDR) Escherichia coli isolate from urine sample of UTI patient. The clinical isolates of E.coli was obtained from 5 out of 10 urine samples of Urinary Tract Infection (UTI) patients using Hicrome UTI agar. The isolate was checked for their resistance, by using antibiotic susceptibility test. The multidrug resistant (MDR) isolate was further subjected to phage susceptibility test using lambda phage and phages isolated from sewage. The lambda phage and phages isolated from sewage was found highly lytic to MDR E.coli. Phage therapy can be used for treating MDR E. coli and can even compensate the progressively failing antibiotics.
Authors and Affiliations
Rima Das, Anusha Balasingh, Anupama R
Keywords
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