BIOCHEMICAL PROFILE AND VARIOUS TREATMENT MODALITIES OF PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH)
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 17
Abstract
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is an increasingly recognized condition that may progress to end stage liver disease. Although non-alcoholic steatohepatitis (NASH) was considered relatively uncommon prior to middle of last decade, over the past few years there has been an explosion of studies on various aspects of NASH with one study reporting that after hepatitis C, NASH was the most common diagnosis in patients presenting largely with persistent abnormalities of liver function tests. We wanted to study the biochemical profile and various treatment modalities in patients of non-alcoholic steatohepatitis (NASH). METHODS The present study was carried out on 60 patients of NASH over a period of one year at Pathology Department of GMC, Jammu, which is a tertiary care centre. All patients with NASH were screened for various risk factors associated with NASH. Detailed history was taken, and thorough clinical examination was done. Required investigations were done such as Hb, TLC, DLC, blood sugar, renal function tests, complete liver tests, serum lipid profile, viral markers (HBsAg and Anti-HCV) and ANA. Ultrasound abdomen for hepatobiliary system was done to diagnose the patients of NASH. RESULTS Out of 60 patients, 28 (46.66%) were males and 32 (53.32%) were females. 85% of the patients were in the age group of 31-70 years. Out of 60 patients only 16 patients followed regularly and remained under close supervision. CONCLUSIONS In the present study, it was found that obesity was present in 46.6% cases whereas 50% patients were hyperlipidaemic. 38% patients were suffering from diabetes. It was found that there was marked symptomatic and biochemical improvement in those who were on strict dietary control and on regular follow up.
Authors and Affiliations
Vinod Kumar, Ritu Bhagat
Keywords
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- EP ID EP613563
- DOI 10.14260/jemds/2019/312
- Views 93
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