Bioinformatics: Application of Information Technology in Biological Science
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 2
Abstract
Bioinformatics was applied in the creation and maintenance of a database to store biological information at the beginning of the "genomic revolution", such as nucleotide and amino acid sequences. Development of this type of database involved not only design issues but the development of complex interfaces whereby researchers could both access existing data as well as submit new or revised data. Bioinformatics and computational biology are frequently integrated with experimental studies as well, with bioinformatics emphasizing informatics and statistics, while computational biology emphasizes development of theoretical methods, mathematical modeling, and computational simulation techniques to find solution for genetic problems. Bioinformatics studies include analysis and integration of genomics data, prediction of protein function from sequence, and comparisons of protein ligands to identify target effects of drugs. Computational biology includes simulation of protein motion and folding and how proteins interact with each other.
Authors and Affiliations
Dr. Mohammad Alamgeer
Keywords
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