Bioinformatics: Homology Detection and Protein Families Computation in the Area of New Research
Journal Title: International Journal of Computational Engineering and Management IJCEM - Year 2012, Vol 15, Issue 6
Abstract
It is the name given to these mathematical and computing approaches used to glean understanding of biological processes. It is the application of information technology to the field of molecular biology. Bioinformatics entails the creation and advancement of databases, algorithms, computational and statistical techniques, and theory to solve formal and practical problems arising from the management and analysis of biological data. Over the past few decades rapid developments in genomic and other molecular research technologies combined developments in information technologies have combined to produce a tremendous amount of information related to molecular biology Common activities in Bioinformatics include mapping and analyzing DNA and protein sequences, aligning different DNA and protein sequences to compare them and creating and viewing 3-D models of protein structures. The primary goal of bioinformatics is to increase our understanding of biological processes. What sets it apart from other approaches, however, is its focus on developing and applying computationally intensive techniques (e.g., data mining, and machine learning algorithms) to achieve this goal. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.
Authors and Affiliations
Manjeet Kaur Bedi, Kendar Pratap, Raj Kumari
Keywords
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