Biologic therapy-Related demyelinating peripheral neuropathy in a child with Juvenile Idiopathic Arthritis

Journal Title: Archives of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 2, Issue 1

Abstract

Demyelinating peripheral neuropathy has been described in association with tumor necrosis factor (TNF) inhibitors. It is rarely developed after treatment discontinuation. We present the case of a child with juvenile idiopathic arthritis who developed peripheral neuropathy few months after TNF inhibitor withdrawal with clinical worsening of the neurological sequelae while undergoing treatment with abatacept.

Authors and Affiliations

Heba A Alqurashi, Ghada Al-Salmi, Mohammad A Al-Muhaizea, Sulaiman M Al-Mayouf

Keywords

Related Articles

Some Aspects of medicine distribution in Sudan

The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and...

Sense and antisense Oligodeoxynucleotides to Glun1 Nmdar are Cognitive Enhancers (Nootropics) and protective agents in normal and ischemic (Anoxic) conditions-In vitro study

Aims: Implication of modified N-methyl-D-aspartate receptors (NMDAR) in synaptic plasticity and learning was investigated in normal and pathological conditions. Study design: We studied the efficiency of synaptic plasti...

Paediatric Medicines: Formulation Considerations

The use of unlicensed and off-label medicines in children is widespread and has raised an increasing concern over the last years. The majority of medicines taken by children are extemporaneously compounded by pharmacist,...

Preclinical studies for a cationic liposome formulation containing Il-2 Intended for the treatment of Human Tumors

Human cervical cancer tumours expressing the IL-2 receptor (IL-2R) were induced in the peritoneal cavity of nude mice. The tumours were significantly reduced by the i.p. administration of either free IL-2 or liposomes co...

Diazepam Withdrawal Expression is related to Hippocampal NOS-1 Upregulation

Background: Benzodiazepines are usually prescribed for anxiety and sleep disorders in a long-term fashion that may cause drug dependence. Discontinuation after prolonged administration may lead to withdrawal expression,...

Download PDF file
  • EP ID EP560284
  • DOI 10.29328/journal.apps.1001008
  • Views 58
  • Downloads 0

How To Cite

Heba A Alqurashi, Ghada Al-Salmi, Mohammad A Al-Muhaizea, Sulaiman M Al-Mayouf (2018). Biologic therapy-Related demyelinating peripheral neuropathy in a child with Juvenile Idiopathic Arthritis. Archives of Pharmacy and Pharmaceutical Sciences, 2(1), 20-22. https://europub.co.uk/articles/-A-560284