Biological Efficacy of Quassia Indica (Geratn) Nooteb and Centella Asiatica (L.) Urban Against Selected Strains of Bacteria
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
Antimicrobial activity of different extracts of two selected plants, Quassia indica (Geartn) Nooteb and Centella asiatica (L.) Urban were tested against selected strains of bacteria viz; Escherichia coli, Staphylococcus aureus, Pseudomonas sps, Bacillus thuringiensis, Klebsiella sps and Serratia sps using agar disc diffusion technique. Petroleum ether, acetone, methanol and water extracts of seed and leaf of Q. indica and leaf of C. asiatica showed moderate to significant antimicrobial activity. Of the four extracts tested, petroleum ether and water fractions showed more activity against all the bacterial strains. The zone of inhibition of the active fractions for the petroleum ether ranged from 8.57 to 12.63 mm and 8.53 to 14.5mm for the water fraction of Q. indica seed and leaf and C. asiatica leaf; and exhibited comparable results with widely used commercial antimicrobial agents (16 to19 mm for Kanamycin and 14 to 17mm for Cefotaxime). The results prove the efficacy of the most active fractions of the selected plant extracts to be used for developing potent antimicrobial formulations.
Authors and Affiliations
Aiswarya 1D, E. Pushpalatha2
Keywords
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- EP ID EP388212
- DOI 10.9790/3008-1201029597
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