BIPHENYL SUBSTITUTED CONSTITUENTS FROM THE RHIZOMES OF CURCUMA AMADA ROXB.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 12
Abstract
Phytochemical investigation of the rhizomes of Curcuma amada Roxb. (Zingiberaceae) led to isolation of three new biphenyl substituted hydrocarbons identified as 1- (3’, 4’-dihydroxyphenyl)-8 - ( 3’’, 4’’ - dimethoxy - 5’’ - carboxylic acid phenyl)- octa-cis,cis-1, 4 - diene (amadanoic acid A) (2), 1- (3’, 4’ - dihydroxyphenyl) - 8 - ( 2’’, 6’’- dihydroxy -3’’, 4’’- dimethoxy - 5’’- carboxylic acid) –cis,cis- octa-1,4 - diene (amadanoic acid B) (3) and 1, 15 – dibenzyl – 3 - methyl pentadecane - 4β, 12β –diol (amadandiol) (5) along with the known compounds n-nonacosan-1-ol (1) and curcumin (4) . Their structures were elucidated by combination of chemical tests and spectral data analysis.
Authors and Affiliations
Mustafa Akhlaq , Ali Mohammed
DESIGN AND DEVELOPMENT OF pH-TRIGGERED IN SITU GELLING SYSTEM OF CIPROFLOXACIN
The aim of the present work was formulation and evaluation of in situ gelling system of ciprofloxacin. The poor bioavailability and therapeutic response exhibited by conventional ophthalmic solutions due to rapid precorn...
PHYSICOCHEMICAL ANALYSIS OF WATER OF BAGALKOT DISTRICT, KARNATAKA IN INDIA
Physicochemical analysis such as temperature, pH, Total hardness, Chloride, fluoride, iron, Total Alkalinity, Nitrate, Nitrite and sulfate of bore wells, drinking water has been carried out from twenty sampling stations...
VAJIKARANA: A UNIQUE THERAPY OF AYURVEDA
Ayurved, the science of life deals with every aspect of life and Vajikarana is one of its eight branches being practiced since time immemorial. Ayurveda has two aims i.e. protection and promotion of health and secondly c...
ANTIBACTERIAL POTENTIAL OF GLORY LILY, GLORIOSA SUPERBA LINN.
The successive Soxhlet extract of Gloriosa superba, L. (Liliaceae) was extracted using acetone, dichloromethane, chloroform and methanol in ascending order of the polarity. The extracts were investigated for their antiba...
EVALUATION OF ANXIOLYTIC ACTIVITY OF CARUM COPTICUM BY USING ELEVATED PLUS MAZE AND OPEN FIELD METHOD
The clinical applications of benzodiazepines as anxiolytics are limited by their unwanted side effects. Therefore, the development of new pharmacological agents is well justified. Among medicinal plants, Carum copticum...