BIPHENYL SUBSTITUTED CONSTITUENTS FROM THE RHIZOMES OF CURCUMA AMADA ROXB.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 12
Abstract
Phytochemical investigation of the rhizomes of Curcuma amada Roxb. (Zingiberaceae) led to isolation of three new biphenyl substituted hydrocarbons identified as 1- (3’, 4’-dihydroxyphenyl)-8 - ( 3’’, 4’’ - dimethoxy - 5’’ - carboxylic acid phenyl)- octa-cis,cis-1, 4 - diene (amadanoic acid A) (2), 1- (3’, 4’ - dihydroxyphenyl) - 8 - ( 2’’, 6’’- dihydroxy -3’’, 4’’- dimethoxy - 5’’- carboxylic acid) –cis,cis- octa-1,4 - diene (amadanoic acid B) (3) and 1, 15 – dibenzyl – 3 - methyl pentadecane - 4β, 12β –diol (amadandiol) (5) along with the known compounds n-nonacosan-1-ol (1) and curcumin (4) . Their structures were elucidated by combination of chemical tests and spectral data analysis.
Authors and Affiliations
Mustafa Akhlaq , Ali Mohammed
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