BISPHOSPHONATES AND NEOADJUVANT CHEMOTHERAPY IN PATIENTS WITH BREAST CANCER
Journal Title: Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал - Year 2013, Vol 75, Issue 3
Abstract
the purpose of article was to analyze different trials and to evaluate whether the use of bisphosphonates in complex with neoadjuvant chemotherapy breast cancer patients improve results. The evaluation of randomize and experimental trials shows direct and indirect antitumor effect of bisphosphonates, which was completely connected with synergism of both group medications. Bisphosphonates improves survival breast cancer patients in different investigations of adjuvant gormonotherapy or chemotherapy. It is necessary to organize randomize trial in which neoadjuvant chemotherapy will be use with bisphos- phonates, as was received in the experimental data. Moreover, the synergism of both group medications prognoses better survival in triple negative breast cance
Authors and Affiliations
V. Cheshuk
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