Blood presure variability in patients with obstructive sleep apnea syndrome and heart failure with preserved ejection fraction
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 1
Abstract
The aim of the study was to investigate the features of daily blood pressure changes in patients with obstructive sleep apnea syndrome (OSAS) and heart failure with preserved ejection fraction based on the data of daily blood pressure monitoring. Materials and methods. 86 patients with OSAS and HFpEF (group 1), 74 patients with HFpEF without OSAS (2nd group) and 52 patients with OSAS and without HF (group 3) were examined. All participants of the study underwent cardio-respiratory monitoring, ABPM, echocardiography, NT-proBNP. Results. SABP and DABP in patients with HFpEF and OSAS were generally higher in the day and night than in comparison groups. "Non-dipper" dominated among the pathological daily profiles. As results of the multivariate regression analysis, it was found that the level of SABP at night was determined by IAH (β=0,386, p<0,05) and MeanSaO2 (β=0,339, p<0,05). The DABP level at night was determined by the IAH (β=0.412, p<0.05). Conclusions. Patients with OSAS and HFpEF have insufficient reduction in blood pressure at night and greater variability of blood pressure overnight. With the increase of OSAS severity more often daily profiles "non-dipper" and "night-peaker" are recorded, the variability of blood pressure increases. When performing a multivariate regression analysis, it was found that the level of SABP at night was determined by IAH (β=0,386, p<0,05) and MeanSaO2 (β=0,339, p<0,05); DABP level at night was determined by the IAH (β=0,412, p<0,05).
Authors and Affiliations
I. O. Andreieva, D. P. Myrnyi, M. M. Surmilo
Keywords
Related Articles
- EP ID EP319713
- DOI 10.26641/2307-0404.2018.1(part2).126933
- Views 55
- Downloads 0
Features of the mental status of patients with community-acquired pneumonia, combined with a chronic pathology of the hepatobiliary system of non-viral genesis
The aim was to study the characteristics of mental status of patients with community-acquired pneumonia (CAP), combined with a chronic pathology of the hepatobiliary system of non-viral genesis. We observed 165 patients...
Multigenic forms of thrombophilia in habitual miscarige
Miscarriage is an actual problem of modern obstetrics. The frequency of miscarriage is 10-25% of all pregnancies, and habitual abortion occurs in 5%. Habitual miscarriage is considered as a typical multifactorial d...
Мутація промотора гена синтази оксиду азоту eNOS Т786С у хворих з хибними суглобами довгих кісток: зв´язок з рівнем ліпідів та ендотеліальною функцією судин
Цель работы: изучить распространенность полиморфизма промотора гена eNOS Т786С у лиц с ложными суставами длинных костей и оценить его связь с уровнем липидов и эндотелиальной функцией сосудов. Материалы и методы исследов...
Endothelial function of vessels in patients with chronic kidney disease combined with subclinical hypothyroidism under the influence of combined antihypertensive therapy
The aim of the study: to evaluate the endothelial function of the vessels under the influence of combined antihypertensive therapy (valsartan 160 mg / amlodipine 5 mg vs valsartan 160 mg / hydrochlorothiazide 12,5 mg) in...
Частота, морфологічна характеристика та предиктори організації тромбів вушок передсердь після чотирьох тижнів антикоагулянтної підготовки до планової електричної кардіоверсії фібриляції передсердь
Цель: изучить частоту тромбоза, предикторы организации тромбов в ушках предсердий у пациентов с персистирующей неклапанной фибрилляцией предсердий (ПНФП) при проведении чреспищеводной эхокардиографии (ЧПЭхо-КГ) после 4 н...