Breast Cancer Regulation and Progression: A Review on Genetics and Microenvironment of Breast Cancer
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 1
Abstract
Breast cancer is the most common cancer diagnosed among women. The stromal compartment of the breast includes the extracellular matrix (ECM) and stromal cells. Breast cancer is complicated by unique molecular alterations and interactions of microenvironment cells and extracellular matrix. The aim of this article is to use the literature review on (BC) risk factors, pathological and molecular subtypes. Additionally, to review the progression of (BC) at molecular signatures to address the correlation between the genotypic changes and surrounding breast stroma. The literatures covered in this review have shown that the microenvironment genetic alterations play important role on (BC) progression.
Authors and Affiliations
Zyad Musaad Alsulaiman, Abdulaziz Musaad Alsulaiman, Ali S Alharth
Keywords
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- EP ID EP541022
- DOI 10.21276/ijmrp.2017.3.1.001
- Views 80
- Downloads 0
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