Budget impact analysis of breast cancer in the Russian Federation
Journal Title: JOURNAL OF HEALTH POLICY & OUTCOMES RESEARCH - Year 2016, Vol 9, Issue 1
Abstract
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in the female population of the Russia and its incidence is rapidly growing. Advanced breast cancer is a disease currently intreatable, but up-to-date management strategies result in significant improvement of symptoms, life expectancy and quality of life. Implementation of new technologies always results in extended healthcare expenditures, therefore requiring pharmacoeconomical justification. Russian Society for Pharmacoeconomics and Outcomes Research performed health economics evaluation of typical management strategies of patients with advanced hormone-dependent HER2-negative breast cancer, based on survey of experts. The questionnaire developed for this purpose including data relevant to epidemiological and pharmacoeconomic assessment of management of such patients. Calculation of expenses incurred by medications and medical care was performed based on experts’ data and according to the medical care standard #612н. Markov model in Microsoft Excel® application, as developed by York Health Economics Consortium, was used for pharmacoeconomic analysis. The model was based on approaches to treating patients with breast cancer for the duration of 5 years. Managing postmenopausal patients diagnosed with advanced hormone-dependent HER2-negative breast cancer with and without administration everolimus were assessed as alternative approaches, and the method of health economic analysis of budget impact was used to compare them. According to the analysis results, implementation of everolimus administration in the treatment strategies for postmenopausal patients with advanced hormone-dependent HER2-negative breast cancer does not incur significant increases of healthcare budget expenses in the Russian Federation.
Authors and Affiliations
Pavel Vorobiev, Liubov Krasnova, Malwina Hołownia
Keywords
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- EP ID EP192259
- DOI 10.7365/JHPOR.2016.1.5
- Views 90
- Downloads 0
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