Calcinosis cutis of usual and unusual sites: An eight year retro-prospective study in a tertiary teaching hospital in Western Uttar Pradesh, India
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Calcinosis cutis is characterized by deposition of calcium in the skin. Case reports of calcinosis cutis form a wonderful data in clinical and pathological literature. Aims and Objectives: The aim of the present study was to highlight the various clinicopathological aspects of calcinosis cutis lesions of various sites in our archives. Materials and Methods: We performed an analysis of clinicopathological features of all diagnosed cases of calcinosis cutis from our archives. This was a retro-prospective type of study for eight years i.e. from July 2008- June 2016. Observation and Results: In our study we studied 18 cases of calcinosis cutis from various sites. A few cases were unusual in terms of locations, size and presentation. Most common site was scrotum. Wide surgical excision was the treatment of choice. Histopathological diagnosis was rarely difficult. Histochemical Von Kossa staining was done in all cases for confirmation. Conclusion: The results from the present study displayed the various presentations, locations and variability on histopathological architecture, thus highlighting the various clinicopathological aspects of calcinosis cutis lesions. Special histochemical staining is required for confirmation.
Authors and Affiliations
Alok Mohan, Shruti Singh, Veena K. Sharma, Purva Sharma, Swarn Kaur
Keywords
Related Articles
- EP ID EP312589
- DOI 10.18231/2394-6792.2017.0034
- Views 59
- Downloads 0
Comparison of immunofluorescence assay (IF) with ELISA in detection of antinuclear antibodies
Patients with autoimmune connective tissue diseases often have antibodies that are directed against multiple nuclear antigens called as antinuclear antibodies ANA Two testing methods ie ELISA and indirect immunofluoresce...
Utility of C-Kit Expression by Immunohistochemistry as a Prognostic and Theranostic Marker in Colorectal Carcinoma
Objectives: Targeted therapy is now available for various carcinomas with growth factor receptor mutations. C-Kit, a tyrosine kinase receptor is overexpressed in many epithelial malignancies. The aim of this study is to...
Histopathological study of tonsillectomy specimen in a Tertiary Care Hospital
Aim: To study the spectrum of diseases affecting the palatine tonsils and to establish the histopathological criteria for diagnosis of chronic tonsillitis. Materials and Method: 40 palatine tonsillectomy specimen receive...
Secondary renal amyloidosis complicating psoriatic arthropathy
Introduction Secondary AA amyloidosis is a classical complication of chronic inflammatory conditions like rheumatoid arthritis ankylosing spondylitis and inflammatory bowel disease or chronic infectious diseases like tub...
Histopathological evaluation of cerebral lesions
Introduction A cerebral lesion refers to any type of abnormal tissue found in the brain particularly in the cerebral cortex The cerebrum is responsible for allowing voluntary movements within the human body Cerebral tumo...