Changes in Electrolytes Level and ECG Parameters in Chronic Kidney Disease Patients Post Haemodialysis and the Correlation of Their Changes : A Cross-Sectional Study Done In Karwar, Karnataka
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 5
Abstract
Background: Patients with chronic kidney disease undergoing maintenance haemodialysis have Electrocardiogram abnormalities. Aims & Objectives: To compare the serum electrolytes level and ECG parameters in chronic kidney disease patients pre and post haemodialysis and to cor-relate their changes. Materials & Methods: This cross-sectional study was conducted in KAIMS, hospital over chronic kidney disease patients enrolled for routine haemodialysis. 12- Lead ECG was recorded 4 times over each patient, 1st -15 min prior to haemodialysis, 2nd- 1 hr after the dialysis had begun, 3rd –1 hr later to 2nd recording, 4th -within 10 min post haemodialysis. Two venous blood samples of each patients were drawn one 15 min prior to haemodialysis and another within 10 min post haemodialysis to assess the serum sodium, chloride, potassium, calcium and phosphate levels using semi-autoanalyser. Results: Significant increase in serum Na+ and Calcium levels with significant decrease in serum K+ and phosphate levels were noted post haemodialysis. There was significant decrease in PR interval with significant increase QRS duration. There was insignificant increase in QTc interval. There was highly significant increase in SV1 voltage, Sokolow-Lyon voltage and Sokolow-Lyon product. There was medium significant correlation between rise in heart rate and fall in K+ level and between increase in QRS duration and decrease in serum phosphate level. Conclusion: Patients with chronic kidney disease undergoing maintenance haemodialysis have ECG abnormalities due to electrolyte changes, which would increase the mortality rate among these patients.
Authors and Affiliations
Dr. Prasad B K
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