Chemical screening of some reputed anti-malarial plants Used in Lubumbashi city and its surroundings
Journal Title: PhytoChem & BioSub Journal - Year 2018, Vol 12, Issue 3
Abstract
Background: This work follows the not yet published ethnobotanical survey conducted by Mbuyi et al. (2015), which identified 96 plants used in the malaria burden in Lubumbashi and its surrounding areas in the Haut-Katanga province, DR Congo. Aim: This study aimed to find outeight chemical groups (alkaloids, tannins, flavonoids, saponins, quinones, steroids, terpenoids and anthocyanins) in the 35 plants and to report the presence of cyanogenic heterosids as a toxicity index.Material and methods: Staining, precipitation and foaming reactions were used as reported by Bruneton (2009). Results: The presence of eight chemical groups (alkaloids, tannins, flavonoids, saponins, quinones, steroids, terpenoids and anthocyanins) has been reported in the organs of the 35 plants. Tannins (97.9%) and saponins (92.8%) are the most common while alkaloids (30.6%) and quinones (6.1%) are the least common chemical groups. Chemical screening also revealed the presence of cyanogenic heterosids in only one plant: Stephania abysinica Walp. Among the chemical groups found, some contain molecules having antimalarial properties, like alkaloids such as quinine and tetrandine, terpenoids such as berberine, artemisinin and its derivatives, and quinones. Conclusion: These identified chemical groups would contain molecules with antimalarial activity. Further detailed studies will be helpful in isolating and characterizing them.
Authors and Affiliations
MBUYI KALONJI S, KALUNGA M, CIMANGA CIOTO C, NUMBIWA I, MBAYO K, KAPONDA A, KABADI K, MWAMBA M, KALONDA M, LUMBU S
Keywords
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