Chronic Obstructive Lung Disease in young: Alpha 1 anti trypsin deficiency
Journal Title: Journal of Advances in Internal Medicine - Year 2014, Vol 3, Issue 2
Abstract
Alpha-1 antitrypsin (AAT) deficiency is a clinically under recognized inherited disorder. The main clinical manifestations relate to three separate organs: the lung, the liver, and the skin. In the lung, severe deficiency of AAT predisposes to chronic obstructive pulmonary disease. We present a case of 34 years male with a history of recurrent chest infections in past and treated in the line of bronchial asthma but not relieved. He was admitted on 22nd May 2011 at BPKIHS. He presented with type 2 respiratory failure and had features of severe pulmonary arterial hypertension and left lower lobe pneumonia. The patient got improved with the treatment and is doing well on follow up. The diagnosis should be strongly suspected in patients with history suggestive of bronchial asthma and with obstructive features.
Authors and Affiliations
Subodh Sagar Dhakal*| Department of Internal Medicine, BPKIHS, Dharan, Nepal, Krishna Kumar Agrawal| Department of Internal Medicine, BPKIHS, Dharan, Nepal, Narendra Bhatta| Department of Internal Medicine, BPKIHS, Dharan, Nepal
Keywords
Related Articles
- EP ID EP4788
- DOI http://dx.doi.org/10.3126/jaim.v3i2.14067
- Views 444
- Downloads 23
WHEAT FARMERS' PERCEPTIONS OF SUSTAINABLE AGRICULTURE: THE CASE OF KERMANSHAH PROVINCE OF IRAN
The objective of this study was to investigate wheat farmers' perceptions towards sustainable agriculture. The sample included 140 farmers that were determined using Cochran (1977) formula. The Cronbach’s alpha coefficie...
Wellens’ Syndrome, a case report of an electrocardiographic warning sign
Introduction: Wellens’ syndrome is described as a characteristic biphasic or symmetrical electrocardiographic T-wave inversions in precordial leads seen in a subset of patients with unstable angina. It is associated with...
Demographic Profile and Extra Intestinal Manifestations of Ulcerative Colitis in Nepalese population: Study from TUTH a Tertiary Care Centre, Kathmandu, Nepal
Background and Aims: This study aims at determining the demographic profile and extra-intestinal manifestations of Ulcerative Colitis in the Nepalese patients treated in a tertiary referral centre. Methods: The study was...
Nailfold capillaroscopic findings in patients with Raynaud’s phenomenon: Preliminary report
Back grounds and Aims: Microvascular involvement of nailfold often occurs in systemic rheumatic diseases, especially scleroderma and related conditions. Nailfold capillaroscopy is easily performed non-invasive, simple, r...
Chronic Obstructive Lung Disease in young: Alpha 1 anti trypsin deficiency
Alpha-1 antitrypsin (AAT) deficiency is a clinically under recognized inherited disorder. The main clinical manifestations relate to three separate organs: the lung, the liver, and the skin. In the lung, severe deficienc...