Chronic Obstructive Lung Disease in young: Alpha 1 anti trypsin deficiency
Journal Title: Journal of Advances in Internal Medicine - Year 2014, Vol 3, Issue 2
Abstract
Alpha-1 antitrypsin (AAT) deficiency is a clinically under recognized inherited disorder. The main clinical manifestations relate to three separate organs: the lung, the liver, and the skin. In the lung, severe deficiency of AAT predisposes to chronic obstructive pulmonary disease. We present a case of 34 years male with a history of recurrent chest infections in past and treated in the line of bronchial asthma but not relieved. He was admitted on 22nd May 2011 at BPKIHS. He presented with type 2 respiratory failure and had features of severe pulmonary arterial hypertension and left lower lobe pneumonia. The patient got improved with the treatment and is doing well on follow up. The diagnosis should be strongly suspected in patients with history suggestive of bronchial asthma and with obstructive features.
Authors and Affiliations
Subodh Sagar Dhakal*| Department of Internal Medicine, BPKIHS, Dharan, Nepal, Krishna Kumar Agrawal| Department of Internal Medicine, BPKIHS, Dharan, Nepal, Narendra Bhatta| Department of Internal Medicine, BPKIHS, Dharan, Nepal
Keywords
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- EP ID EP4788
- DOI http://dx.doi.org/10.3126/jaim.v3i2.14067
- Views 457
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