Chronic Progressive External Ophthalmoplegia A Rare Case Report
Journal Title: PARIPEX-Indian Journal of Research - Year 2015, Vol 4, Issue 5
Abstract
Chronic progressive external ophthalmoplegia (CPEO), also known as progressive external ophthalmoplegia (PEO), is a type of eye disorder characterized by slowly progressive inability to move the eyes and eyebrows.[1] It is often the only feature of mitochondrial disease, in which case the term CPEO may be given as the diagnosis. In other people suffering from mitochondrial disease, CPEO occurs as part of a syndrome involving more than one part of the body, such as Kearns-Sayre syndrome. Occasionally CPEO may be caused by conditions other than mitochondrial diseases. A woman aged 20years presented with history of drooping of both eyelids started 07 years back . No history of fatiguability , fluctuations in drooping of eyelids. No H/O consanguinity. Neurological examination showed moderate bilateral ptosis and marked limitation of conjugate gaze in all direction. Serum acetylcholine receptor antibody was negative. Neostigmine test was negative. MRI brain normal. Repetitive nerve stimulation test showed no decremental response both at rest and post exercise. Histopathological examination of biopsy specimen from left quadriceps revealed Ragged red fibres on Modified Gomari Trichome (MGT) stain ,suggestive of mitochondrial myopathy - CPEO.
Authors and Affiliations
Dr. C. Sreenivasulu, Dr. G. Shaul Hameed, Dr. T. Vinil
Keywords
Related Articles
- EP ID EP572263
- DOI -
- Views 107
- Downloads 0
HEPATOPROTECTIVE EFFECT OF ECLIPTA ALBA AND PHYLLANTHUS FRATURNUS EXTRACT IN ANIMAL MODEL (RATS)
This exercise was undertaken to study the hepatoprotective effect of Eclipta Alba and Phyllanthus fraturnus extract in CCl4 treated rats. CCl 4 induced fatty liver and liver cell necrosis in the rats. 60 male albino rats...
METACOGNITION AND MULTIMEDIA BASED TEACHING ON ACHIEVEMENT IN MATHEMATICS OF STANDARD XI STUDENTS
This study was conducted to find the relationship between metacognition and post test scores of control group and experimental group students of standard XI. The investigator developed a multimedia based content with spe...
Comparison of Subjective Success of Extirpative and Obliterative Methods in the Treatment of Pelvic Organ Prolapse Among Elderly Patients
Aim: This study aimed to compare the effects of surgical treatment methods of Pelvic Organ Prolapse, vaginal hysterectomy and colpocleisis, on quality of life in elderly patients. Methods: In this retrospective cohort st...
PREDICTIVE FACTORS FOR IMPROVEMENT OF INTERNATIONAL PROSTATIC SYMPTOM SCORE FOR PATIENTS FOLLOWING TRANSURETHRAL RESECTION OF PROSTATE
Introduction: Prostate is one of the major accessory sex gland of male reproductive system. Benign prostatic hyperplasia (BPH) is one of the most common problems of aging males all over the world. Benign prostatic hyperp...
Traumatic Cerebellar Hematoma: A Single Institute Experience
Background-Traumatic cerebellar hematoma(TCH)is rare, but they are important cause of morbidity and mortality. Method-Thisretrospective study was conducted over two years on patients of head injury at a tertiary care cen...