Clinical advancement in Rheumatoid Arthritis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Rheumatoid arthritis (RA) is an autoimmune disorder that mainly affects joints. The cause of RA is believed to be a combination of genetic and environmental factors. Family history of RA increases the risk around three to five times. Smoking,Caucasian populations, increasing risk of RA.Periodontal disease has been associated with RA.Disease progresses as phase 1,non-specific inflammation to phase 2, amplification in the synovium to phase 3 or chronic inflammation. RA primarily affects joint, rheumatoid nodule in the skin, lung fibrosis, atherosclerosis and risk of myocardial infarction. Diagnosis includes X-rays and imaging, laboratory tests, using diagnostic criteria, and excluding other medical conditions. There is no cure for RA,treatment can improve symptoms and slow the progress of the disease, change in lifestyle, regular exercise and use of disease modifying anti-rheumatic drugs(DMARDs).Surgery may be necessary for affected fingers, hands, and wrists, synovectomy may be needed to prevent pain or tendon rupture. A review of CAM(complimentary alternative medicine)(excluding fish oil),does not support their current use in the management of RA. Some evidence supports omega- 3 fatty acids and gamma-linolenic acid in RA. Tai Chi improves joint motion, but acupuncture inconclusive. RA reduces lifespan from three to twelve years, and double risk of heart disease.There is no known prevention other than reduction of risk factors
Authors and Affiliations
Murtaza Mustafa,, HM. Iftikhar2, EM . illzam, AM. Sharifa, ,MK . Nang
Keywords
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- EP ID EP362953
- DOI 10.9790/0853-1702085561
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