Clinical advancement in Rheumatoid Arthritis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Rheumatoid arthritis (RA) is an autoimmune disorder that mainly affects joints. The cause of RA is believed to be a combination of genetic and environmental factors. Family history of RA increases the risk around three to five times. Smoking,Caucasian populations, increasing risk of RA.Periodontal disease has been associated with RA.Disease progresses as phase 1,non-specific inflammation to phase 2, amplification in the synovium to phase 3 or chronic inflammation. RA primarily affects joint, rheumatoid nodule in the skin, lung fibrosis, atherosclerosis and risk of myocardial infarction. Diagnosis includes X-rays and imaging, laboratory tests, using diagnostic criteria, and excluding other medical conditions. There is no cure for RA,treatment can improve symptoms and slow the progress of the disease, change in lifestyle, regular exercise and use of disease modifying anti-rheumatic drugs(DMARDs).Surgery may be necessary for affected fingers, hands, and wrists, synovectomy may be needed to prevent pain or tendon rupture. A review of CAM(complimentary alternative medicine)(excluding fish oil),does not support their current use in the management of RA. Some evidence supports omega- 3 fatty acids and gamma-linolenic acid in RA. Tai Chi improves joint motion, but acupuncture inconclusive. RA reduces lifespan from three to twelve years, and double risk of heart disease.There is no known prevention other than reduction of risk factors
Authors and Affiliations
Murtaza Mustafa,, HM. Iftikhar2, EM . illzam, AM. Sharifa, ,MK . Nang
Keywords
Related Articles
- EP ID EP362953
- DOI 10.9790/0853-1702085561
- Views 66
- Downloads 0
A Randomized Controlled Trial Comparing the Efficacy of Atorvastatin and Metformin in the Patients with Polycystic Ovary Syndrome
INTRODUCTION: Polycystic ovary syndrome(PCOS) may be associated with overweight and obesity,hyperandrogenism, insulin resistance and impaired glucose tolerance, anovulation and infertility and abnormal lipid profile. Aim...
TB or Not TB- That is the Question: Misdiagnosis of Spinal Metastasis As Tuberculosis Spine
Introduction: Due to the increased prevelance of Tubeculosis and the practical acceptance of Trial Anti Tubercular Therapy (ATT), it is the first diagnosis that comes to our mind while anaplastic conditions are our last...
Histopathological Spectrum of Ophthalmic Lesions- A study of 53 cases
Ophthalmic lesions include a wide spectrum of conditions ranging from benign lesions and malignant lesions. The diagnosis of these lesions is based on the clinical as well as histopathological features. This was a retros...
Method Development And Validation for the Simultaneous Estimation of Atazanavir And Ritonavir in Tablet Dosage Form By Rp-Hplc And Uv Spectrophotometry
An accurate, precise, rapid and robust RP-HPLC and UV methods were developed and validated for the simultaneous estimation of Atazanavir and Ritonavir in tablet dosage forms. The chromatographic separation was carried ou...
Gene therapy: Recent development, benefits and pitfall
Abstract: The use of gene therapy technology to treat genetic diseases has achieved great success in last few years. The advance in biotechnology field provides much hope for the future of gene therapy and made this meth...