Clinical and Bacteriological Profile of Patients Admitted to ICU with Community Acquired Pneumonia in a Tertiary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Introduction: Community acquired pneumonia (CAP) causes significant mortality and morbidity all over the world, especially in developing countries like India. There is scarce data on the bacteriological profile in patients admitted to ICU from South India so it is necessary to study the clinical and bacteriological profile of these patients for better understanding and treatment of pneumonia. Methodology: We conducted a prospective study in department of Pulmonology in a tertiary care centre during October to December 2017. Consecutive patients admitted with community acquired pneumonia (CAP) were included in the study after obtaining informed consent. Patients with Hospital acquired pneumonia, Health care associated pneumonia were excluded from the study. All patients were interviewed with questionnaire, which included demographic data, risk factors like smoking and alcoholism, comorbidities, number of admissions, emergency visits, use of intravenous or oral antibiotics in past, respiratory past medical history such as COPD, bronchiectasis and asthma. Results: 70 patients were included into study. Mean age of the cohort was 42.5±10.2 years and 45 (64.28%) of them were men. More than half the populations (52%) were chronic smokers. COPD (20%) was the most common comorbidity. Of 70 patients, 15(21.4%) patients needed invasive mechanical ventilation, 12% needed inotropes and 10% needed non-invasive ventilation. We could identify causative organisms in around 52.8% of patients. Pseudomonas aeruginosa (12/37) was the most common organisms isolated. We found that Pseudomonas aeruginosa had high resistance to Levofloxacin (94%), Azithromycin (90%), Amikacin (40%) and Pipercillin-Tazobactum(40%). Conclusion: We found in our study gram negative organisms to be most common organisms causing CAP. Pseudomonas aeruginosa was the most common organism isolated in patients admitted to ICU with CAP. We also observed high rate of resistance to commonly used antibiotics.
Authors and Affiliations
Dr Mahendra M
Keywords
Related Articles
- EP ID EP492643
- DOI -
- Views 58
- Downloads 0
Intraepithelial Carcinoma of the Limbus
Ocular neoplasms are uncommon. Of the ocular neoplasms, squamous epithelial tumours of the conjunctiva and cornea are rare. Ocular surface squamous neoplasia is categorized into carcinoma in situ and squamous cell carcin...
Arsenic- Exposure, Mechanism of Action and Toxicity Analysis: A Prenatal View
Arsenic continues to poison the drinking water of thousands across the globe. Numerous studies have evaluated the carcinogenic potential of lifetime exposure and also the ill effects of prenatal exposure. Population Stud...
Socio-demographic correlates of HIV-TB Co-infected Patients Attending ART Centre of Jharkhand
Background: The HIV epidemic has posed a major challenge to control tuberculosis (TB) across the world. HIV and TB both primarily affect people in their most productive years of life. Objectives: This study was done aimi...
Kodameae Ohmeri Fungemia in a Premature Neonate – A Case Report
Kodameae ohmeri is a yeast-like fungus and is considered as an emerging pathogen. This yeast-like fungus has been isolated previously from pleural fluid and blood samples in people with a compromised immune status such a...
Comparative Trial of Phenobarbitone vs Phenytoin in Moderate and Severe Perinatal Asphyxia in Term Neonates
A prospective, hospital-based open-label randomised trial was conducted with primary aim to compare the clinical seizure control after administration of either drug, Phenobarbitone or Phenytoin in term neonates with mode...