Clinical and Clinico-pathological Impacts of Upper Gastrointestinal Bleeding in Elderly Egyptian Patients
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
:Gastrointestinal (GI) bleeding in elderly is a common problem with numerous causes. The study included 120 patients who attended gastrointestinal endoscopic unit, SayedGalal Hospital, Al-Azhar University, Cairo, Egypt suffering from upper gastrointestinal bleeding. Patients were divided into 2 groups (n=60): Group I: below 55 and Group II: above 55 years. Sixty percent of elderly group presented with hematemesis and melena while 40% with melena. The present study revealed that esophagealvarices were responsible for 45% deaths of elderly patients with upper gastrointestinal bleeding. In an attempt to predict the factors which affect the prognosis or outcome of patients with acute variceal bleeding in elderly patients, it was found that patients aged 65 years or less had significant good prognosis and outcome than above 65 years. As regards the residence, history of bilharziasis and Hepatitis C virus (HCV) infection in elderly group, there was a significant relation between them and complications of upper gastrointestinal bleeding (rebleeding and death). Presentation as hematemesis and/or melena had insignificant effect on the prognosis and mortality. There was no significant difference between elderly group I and middle aged group II with respect to white blood cell (WBC) or red blood cell (RBC)`counts. Moreover, hemoglobin and platelets counts did not differ. Liver and kidney functions also did not show any significant difference between the two groups.
Authors and Affiliations
Said Ibrahim Shalaby, Mohamed Abo- Eldahab2, Hesham Abd- Elhafeez2, Abdel Kade r Awad3, Medhat Attia4, Neelima Gupta5 *
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