Clinical case of compensatory nodular hyperplasia
Journal Title: Сучасна гастроентерологія - Year 2019, Vol 0, Issue 1
Abstract
Despite the fact the benign liver neoplasms are relatively rare diseases, a clinician should be aware of such typical benign liver damage as focal nodular hyperplasia (FNH). The article presents a case report of a 36-year-old female who didn’t present with any typical complaints at the time of the examination. The results of computed tomography, puncture liver biopsy with histological and immunohistochemical studies confirmed the FNH diagnosis. The evidence-based recommendations of the European Association for the Study of the Liver (EASL) have been presented, that outlines data on the FNH diagnosis, methods of treatment, and follow-up of patients with this pathology. The FNH is considered to be a proliferative cell response to an aberrant dystrophic artery and can be associated with other conditions characterized by arterial damage, such as hereditary haemorrhagic telangiectasia or previously treated solid tumors in children. FNH is a polyclonal hepatocellular proliferation, considered as a hyperplastic reaction resulting from arterial malformation. Multiple FNHs can be observed in specific clinical context, especially in patients with underlying vascular liver diseases, such as Budd-Chiari syndrome, obliterative portal venopathy and congenital disorders, including hereditary haemorrhagic telangiectasia, portal vein agenesis. No sufficient data in favor or against the planned FNH surgical treatment available, but in the absence of symptoms and taking into account the rarity of complications, a conservative approach is recommended. The surgical treatment is only pursued in exceptional cases (for example, in case of the formation on a growing stalk or exophytic hyperplasia) and liver resection is the treatment of choice.
Authors and Affiliations
N. B. Gubergrits, O. О. Dyadyik, N. V. Bieliaieva, P. G. Fomenko, Yu. E. Chyrkov, S. O. Shpak
Keywords
Related Articles
- EP ID EP508333
- DOI 10.30978/MG-2019-1-59
- Views 109
- Downloads 0
The ways of antihelicobacter therapy in Ukraine (based on the data of analysis of the Ukrainian Registry Hp-EuReg — UKRAINE)
Objective — to assess the state of affairs in the diagnosis and treatment of Helicobacter pylori infection in Ukraine and their conformity with the modern international recommendations. Materials and methods. The perfor...
Clinical case of compensatory nodular hyperplasia
Despite the fact the benign liver neoplasms are relatively rare diseases, a clinician should be aware of such typical benign liver damage as focal nodular hyperplasia (FNH). The article presents a case report of a 36-yea...
Dermatological paraneoplastic syndromes in gastroenterology: prediction of the inevitable or guidance to action? Part I
This article presents information on paraneoplastic syndromes (PNS) — various pathologies and conditions that accompany and sometimes precede the onset of malignant visceral neoplasms. Although some of the PNS and neopla...
Non-invasive diagnosis of non-alcoholic fatty liver disease: the available opportunities we have today
Non-alcoholic fatty liver disease (NAFLD) is becoming an increasingly common disease, it is currently diagnosed in more than a quarter of adult population worldwide, and its portion in the overweight patients with type 2...
Functional intestinal symptoms in patients with inflammatory bowel disease: recommendations of the American Gastroenterological Association (2019)
The paper presents overview of the latest recommendations of the American Gastroenterological Association on the management of patients with functional intestinal symptoms (FIS). It was noted that the prevalence of irrit...