Clinical Features and Treatment of Spinal Myxopapillary Ependymoma: A Series of 15 Cases
Journal Title: Journal of Neurological Sciences-Turkish - Year 2012, Vol 29, Issue 4
Abstract
Background: Myxopapillary ependymoma is a rare ependymoma arising almost exclusively from the filum terminale. Spinal myxopapillary ependymoma (SME) is even rarer. However, up to now there has been no ideal treatment for SME. Methods: The patients received surgical removal from January 2000 to December 2009.Clinical presentation, diagnose, treatment, therapeutic outcome and follow-up results of 15 patients, who were pathologically diagnosed with SME, were retrospectively studied. Results: The patients included eleven males and four females, with an age range of 13 to 57 years (mean 36.5 years). The length of follow-up was determined from the date of surgery to the patient's most recent clinic visit. Histological examinations showed WHO grade â… myxopapillary ependymomas. Gross total removal was achieved in seven patients, piecemeal total removal in two patients, and subtotal removal in six patients. Eight patients were neurologically preserved with Frankel Grade E one year later. Three patients who had recurrence of the tumor for this operation had no improvement after the subtotal resection. There was no tumor recurrence during the follow-up. There was no death in this group. Conclusions: The onset of SME is not characteristic, so pristine diagnosis is very important. Surgery is the routine treatment for SME; gross total removal has better outcomes than piecemeal total removal and subtotal removal. Subtotal removal is achieved in the patients who have the recurrence before this operation. They have no improvement until the recent follow-up. This study provides some directions for further research and treatment of SME.
Authors and Affiliations
Jie LI, Shi-Ting LI, Ming-Jie ZHU, Yong-Min LI, Xu WANG, YU-JUN LI, Xiao-Qiang WANG
Keywords
Related Articles
- EP ID EP98370
- DOI -
- Views 86
- Downloads 0
Thoracic 1-2 Disc Herniation : Case Report
Upper thoracic disc herniations are rare. Their clinical manifestations may be confusing. The dermatomal involvement in T1-2 and C7-T1 herniations may be similar and causes difficulties in the diagnosis. In this study, t...
Surgical Management of Single and Multiple Brain Metastases
The aim of this study was to assess importance of the surgery among the treatment modalities for patients with brain metastasis (BM). Retrospective review of 48 BM patients newly diagnosed at our neurosurgery clinic betw...
Superficial Siderosis Due To Third Ventricular Cavernous Malformation: Case Report
Cavernous malformations can be seen anywhere in the central nervous system. However their existence in intraventricular area is very rare. Superficial siderosis is an extensive deposit of hemosiderin the leptomeninges an...
The Diagnostic Value of Semmes-Weinstein Monofilaman Test in Diagnosis of Carpal Tunnel Syndrome
The aim of the current study was to investigate the sensitivity and spesificity of Semmes-Weinstein monofilament test in diagnosis of carpal tunnel syndrome. Totally fifty patients and their eighty five hands were includ...
Gadolinium Enhancement of Cerebrospinal Fluid on Flair Sequence in A Patient With Chronic Renal Failure
On Fluid-attenuated inversion recovery (FLAIR) sequence, the cerebrospinal fluid signal is nulled, allowing better analysis of adjacent tissue. In some pathologies such as subarachnoid haemorrhage, menengitis, and sagitt...