Clinical Profile of MDR Tuberculosis Patients Attending Tertiary Care Centre, S.N Medical College, Agra
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 6
Abstract
Abstract: Emergence of drug resistant tuberculosis, particularly multi drug resistant TB (MDR-TB) and extensively drug resistant TB (XDR-TB) has become an obstacle to effective TB control in India. The study aims to find out the sociodemographic and clinical profile of MDR-TB patients in DR-TB Centre, Agra. It was a Retrospective Study carried out from March 2016 to March 2017. Out of 234 admitted cases, majority (48.00%) were between 18-50 years. Males were predominant (58.12%). Most patients (61.96%) were underweight (BMI<18.5kg/m2). Among the patients, HIV seropositivity and MDR-TB was found in 8.97% each. A very high default rate was present (20.51%) and a cure rate of 43.59%. The commonest associated co morbidity was Diabetes Mellitus (20.94%). Most patients had moderately extensive (52.99%) lesions in chest x-ray. Relapse of previous antituberculosis treatment was found to be major contributor of MDR-TB suspect as 96.58% had taken ATT previously. Early diagnosis of drug resistance, quality DOTS services and rational use of anti-TB drugs can prevent emerging of MDR-TB as a major public health problem. Adequate dose, adequate duration and Adequate Regimen are the key to success in the treatment of Tuberculosis and prevention of drug Resistance.
Authors and Affiliations
Dr. Santosh Kumar, Dr. Gajendra Vikram Singh, Dr. Benhur Joel Shadrach, Dr. Rishabh Goel, Dr. Chandrakant Kachru Khandare
Keywords
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