Clinical Study of Soft Tissue Sarcoma Cases in A South-Indian Teaching Hospital
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 5
Abstract
Background: The purpose of present study is to know the incidence, clinical presentation and management of soft tissue sarcoma cases and to observe the outcome of the same. Extremity swellings are suspected to be Mesenchymal origin but other areas like Trunk, abdominal wall, Retro peritoneum also may be sites for Soft tissue Sarcomas. The pathological diagnosis by careful tissue study is pivotal. Early recognition, correct histological diagnosis by dedicated Pathologist and early surgical intervention are the most important points regarding the prognosis for the patient which is otherwise very gloomy. Methods: A prospective study of Soft tissue sarcomas in patients attending Government General Hospital, under Rangaraya Medical College has been undertaken from 2012 to 2014. Forty-six patients with softtissue sarcomas have been included in the study. out of which 28 Male and 18 female patients were proved to be having Soft Tissue Sarcomas at various sites. Core-needle biopsy showing Soft-tissue sarcoma of various cell types in both sexes have been included in the study, Exclusion criteria are patients reluctant for follow-up. Results: 46 patients of various age groups were selected .The peak incidence is between 3rd to 6th decades.The site of Sarcomas have been recorded to be extremities (50%), Trunk (23%), Viscrea(13%) and Retroperitoneum(10%), have been in that order the site of Sarcomas.Most common presentation is Asymptomatic swelling followed by recurrent swelling.Wide excision with Post-operative radiotherapy is the most common management protocol that was followed. Conclusions: Soft tissue sarcomas are a group of lesions that arise from the extra Skeletal connective tissue of the body. They include all the non epithelial extra skeletal tissues with the exception of glia of central nervous system, reticulo endothelial system and the supporting tissue of various parenchyma organs. A high index of suspicion with a Histopathological study is very important. Soft tissue imaging with MRI is an important pre-operative investigation to determine the extent, integrity and neurovascular involvement. Incision is to be well planned to include the entire swelling .A size more than 5 centimetres, infiltration into surrounding structures, involvement of neurovascular bundle, enlargement of locoregional lymph nodes are all signs of high risk and poor prognosis. A wide local excision with tumour free margins is very important as local recurrences are to be avoided. Post operative follow up is mandatory and moderate to poorly differentiated sarcomas need Local radiotherapy and chemotherapy.
Authors and Affiliations
Dr. D. Abhivardhan
Keywords
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