Clinical Symptoms and Therapies for Multiple Sclerosis
Journal Title: JOURNAL OF PHARMACEUTICAL TECHNOLOGY, RESEARCH AND MANAGEMENT - Year 2015, Vol 3, Issue 1
Abstract
Multiple Sclerosis (MS) is a chronic form, progressive and immune mediated central nervous system disorder that affects both adults and children. MS is characterized by the development of multiple lesions with the nerve fibers in the spinal cord, optic nerves and brain. Multiple sclerosis affects the approximately 2.5 million people worldwide. A triad of symptoms characterize the disease: fatigue, changes in sensation, ataxia, muscle weakness, dysarthria, dysphagia, visual problems, chronic or acute pain, difficulties of bladder and bowel. The diagnosis of Multiple Sclerosis is made on the foundation of the signs and symptoms, with magnetic resonance imaging and additional laboratory tests playing a helpful role. Every tests are non precise and simply supply supportive indication for diagnosis. A few people have a inadequate number of “relapses” or “attacks” and remain fairly healthy for decades, others may worsen rapidly from the time of analysis, through shortened lifespan and poor excellence of the life. The prognosis is problematical to forecast; it depends on the initial symptom, subtype of the illness, the individual patient’s disorder characteristics. The substantial variability in multiple sclerosis manifestations leads to elevated figure of misdiagnoses each year, but advances in knowledge and pharmaceuticals are leading to more exact identification and successful management. Early diagnosis and management is essential in reducing the severity of disease.
Authors and Affiliations
Ashwani Arya , Sahil Kumar , Rakesh K Sindhu
Keywords
Related Articles
- EP ID EP596701
- DOI 10.15415/jptrm.2015.31003
- Views 124
- Downloads 0
Investigation of the Effects of Cellulose Derivatives on the Kinetics of Drug Release from Cellulose-Based Hydrogel Using a Response Surface Method
The aim of this work was to investigate the effects of the nature and concentration of cellulose derivatives on the release kinetics of ibuprofen from hydrogel matrices using a response surface method (RSM). A series of...
Modified Excipients in Novel Drug Delivery: Need of the Day
Drug products not only contain “actives” that confer the intended therapeutic benefits such as pain relief or act on particular part of the body, but contain other materials that are also “functional” with respect to the...
Assessment of Suspending Properties of Katira Gum: Formulation and Evaluation of Nimesulide Suspension
There are several hydrophilic polymers that have been employed as suspending agents in pharmaceutical suspensions due to their ability to form colloidal gel in aqueous medium. In the present study, katira gum obtained fr...
Neuropharmacological Activities of Abies pindrow Aerial Parts in Mice
The methanol extract (200 or 400 mg/kg, p.o.) and ethyl acetate fraction (25 or 50 mg/kg, p.o.) of A. pindrow aerial parts were screened for anticonvulsant, antidepressant, locomotor, hypnotic and antistress activities....
Estimation of Total Phenols and Flavonoids in Selected Indian Traditional Plants
Traditionally, aerial parts of Abies pindrow Royle (Himalayan Fir; Pinaceae); Abies webbiana Lindl. (Talispatra; Pinaceae); Cephalandra indica Naud. (Ivy Gourd; Cucurbitaceae) and roots of Calotropis gigantea (L.) Dryand...