Clinicopathological profile of mediastinal masses in a tertiary care hospital of Eastern India
Journal Title: International Journal of Medical Research and Review - Year 2018, Vol 6, Issue 8
Abstract
Introduction:The Mediastinum is the central part of thorax where various organs are located which gives rise to various neoplastic and non- neoplastic lesions.Accurate diagnosis is important to formulate proper therapeutic strategy and predict prognosis. Studies are very few in this part of the country. Objective: To analyse presentation of patients with Meditastinal Mass and to classify according to the location of mass. Also, to document Malignant versus Non-malignant nature oflesions. Methods: Total 33 patients with mediastinal masses diagnosed by Imagingand Histopathological study were taken up consecutively in the study during one year of study. Results: of the 33 cases, 21 were male (63.6%) and 12 were female (36.4%), Male; female ratio being 1.8: 1. Age ranged from 14 years to 72 years maximum of 8 Patients (24.2%) in the 12-20 years of age group. 57% of the masses were malignant and 43% were benign. Most common lesion was Lymphoma in 10 cases (30.3%) followed by8 cases of Thymic tumours (24.2%). Metastatic Carcinoma was found in 6 patients (18.2%) followed by 3 patients of Germ cell tumours.One case each of Neurofibroma, Neurolipoma and 6 are of different less common category. Compartment wise, 9 cases (27.3%) were in Anterior Compartment, 1 (3%) case in Post Compartment, 3 case in superior mediastinum, 6 case in Middle mediastinum. Maximum cases, 14(42.5%) were occupying Multiple Compartments. Most common symptom was cough (72%). Pleural and Pericardial effusions were common complication of malignant lesions contributing 7 out of 19(36%) and 3 out of 19(17%) respectively. Conclusion: Mediastinal masses creates a diagnostic dilemma to the clinician. Uncommon cause of common symptoms like cough and common presentation of pleural or pericardial effusion may have Mediastinal mass behind the screen.
Authors and Affiliations
Bikram Kr Saha, Biswajit Saha, Debasis Sarkar, Srabani Chakrabarti, Sibasish Bhattacharya, Ramtanu Bandyopadhyay
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